Results 151 to 160 of about 3,066,252 (313)
Distribution of HLA Tissue Groups in Patients with Gastric Cancer
Eurasian Journal of Medicine, 2019 Objective: Gastric cancer is an important disease that is seen all over the world and that threats public health. At the same time, gastric cancer is a heterogeneous disorder with multifactorial etiologies.
Mehmet Bilici +5 more
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Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma
Brain Pathology, EarlyView.Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.
Rachel Barboza +8 more
wiley +1 more source
Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source
The influence of HLA matching on graft survival in lung transplant recipients is indication specific: a UNOS database analysis. [PDF]
Eur Respir JOtunla AA +8 more
europepmc +1 more source
Cancer Science, EarlyView.The gut microbiota metabolite indole ‐ 3 ‐ propionic acid（IPA) enhanced the inhibitory effect of SCB on tumor growth in HCC mice. IPA upregulated IL‐12A expression through facilitating acetylation of H3K27 in DCs. IPA elevated IL‐12A expression in DCs to promote CD8+ T cell anti‐tumor immunity and ultimately enhances the efficacy of SCB therapy against
Rui Zhao +7 more
wiley +1 more source
HLA-A, -B, and DR Mismatch and Outcomes After Simultaneous Pancreas-Kidney Transplantation in the Modern Era. [PDF]
Clin TransplantSachdeva M +7 more
europepmc +1 more source
scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker
Cancer Science, EarlyView.Single‐cell sequencing of GC analyzed the tumor microenvironment and discovered the C1QA+ TAMs subpopulation with immunosuppressive function. The role of C1q in the prognosis and diagnosis of GC was demonstrated through plasma and tumor tissue from the GC cohort.
Saisai Gong +6 more
wiley +1 more source
The Central Role of HLA Class II-Restricted Helper Neoantigen Vaccines in Cancer Immunotherapy. [PDF]
Cancers (Basel)Morisaki T, Morisaki T.
europepmc +1 more source
Cancer Science, EarlyView.A rapid and efficient CRISPR‐mediated gene editing platform for TIL engineering identified FAM84B as a novel potential target to enhance antitumor activity and pioneered the use of CBE to generate FAM84B loss‐of‐function TIL with enhanced antitumor activity.
Fenge Li +13 more
wiley +1 more source