CD4+ T Cells Predict Relapse in Pemphigus Vulgaris Treated With Rituximab: A Retrospective Study
ABSTRACT Objective This study evaluated the CD4+ T‐cell role in mediating post‐Rituximab Pemphigus vulgaris (PV) relapse, comparing CD4+ count and CD4+/CD20+ ratio between patients who achieved remission and those who relapsed. Methods The clinical course of 27 PV patients treated with Rituximab was evaluated after a 32‐month median follow‐up. CD4+ and
Simone Liguori +9 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
A common network of residue-residue contacts underlies interactions between peptides and HLA class II complex. [PDF]
Kister AE, Leshchiner DR, Kister I.
europepmc +1 more source
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez +16 more
wiley +1 more source
Dendritic cells as orchestrators in the allergen-specific immunotherapy of allergic diseases. [PDF]
Dou X, Gu T, Xu Y.
europepmc +1 more source
Recipient–Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study
In this cohort study of 5033 patients, only the recipient sex, in particularly kidney recipients, was independently associated with an increased risk of infections, when compared to males. These findings indicate that recipient–donor sex combination does not influence short‐term solid organ transplantation outcome.
Christian T. J. Magyar +16 more
wiley +1 more source
Immune cells and rheumatic heart disease: A 2-sample and Bayesian weighted Mendelian randomization study. [PDF]
Xue S, Jiang H, Liu C, Zhou Y.
europepmc +1 more source
HLA Type and the Effect of HLA Antibodies in Kidney, Liver, and Pancreas Transplantation: A Review. [PDF]
Zarei E +7 more
europepmc +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source

