Results 201 to 210 of about 3,066,252 (313)

Scaling of prehospital blood: A model describing impact on U.S. blood donors, distribution and cost

Transfusion, EarlyView.
Abstract Background Prehospital transfusion improves survival in traumatic and medical hemorrhage, but the blood supply implications of scaling this capability across U.S. emergency medical services (EMS) systems are unclear. Study Design and Methods We developed an analytic model incorporating national estimates of prehospital transfusion demand, EMS ...
Pampee P. Young, David Wood, John B. Holcomb, Donald H. Jenkins, Matthew J. Levy   +4 more
wiley   +1 more source

Immunocyte phenotypes underlying the causal autoimmune features in narcolepsy type 1. [PDF]

J Thorac Dis
Li T, Chen Y, Zhang P, Zhu Q, Lin Z, Peng B, Qin R, Steenbergen N, Hu R, Qin H, Zhang X.   +10 more
europepmc   +1 more source

The lymphocyte function of allogeneic peripheral blood stem cell grafts is associated with relapse and cytomegalovirus reactivation

Transfusion, EarlyView.
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) is a treatment primarily for hematological malignancies. Infections, relapse, and graft versus host disease (GvHD) are some of the most common adverse events following HSCT. We aimed to evaluate whether the lymphocyte function of the stem cell graft was associated with these ...
Anna Söderström, Tengyu Wang, Johan Törlén, Hannes Lindahl, Davide Valentini, Stephan Mielke, Klara Asplund Högelin, Rebecca Axelsson Robertson, Michael Uhlin   +8 more
wiley   +1 more source

Intrinsic tumor cell line immunogenicity may drive CAR-independent T cell responses and confound CAR T cell preclinical modeling. [PDF]

J Immunother Cancer
Sheng MK, Firoz WA, Loi K, Vick LV, Collins CP, Nielsen RN, Schmeling JL, Gulati S, Judge SJ, Canter RJ, Monjazeb AM, Zamora AE, Murphy WJ.   +12 more
europepmc   +1 more source

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain, Sukyung Kim, Md Tareque Aziz, Izaz Ahmed, Md Sarower Hossen Shuvo, Hyewon Yang, Yunjeong Jang, Minseo Kim, Seohyeon Jang, Yusol Kim, Soeun Oh, Yunseo Nam, Hoonhee Seo, Ho‐Yeon Song   +13 more
wiley   +1 more source

Is the HLA System Really Involved in Implantation, Pregnancy, or Abortion of the Fetus?: Strengths, Weaknesses, and Controversial Points. [PDF]

Am J Reprod Immunol
Hita A, Botella C, Galian JA, González-López R, Fernández-González M, Alegría-Marcos MJ, Moya-Quiles R, Martínez-Banaclocha H, Muro-Pérez M, Muro J, Minguela A, Legaz I, Muro M.   +12 more
europepmc   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Immune Checkpoint Inhibitor Resistance in Rectal Adenocarcinoma Containing a Mismatch Repair Deficiency Component: A Case Report. [PDF]

Cancer Diagn Progn
Okura K, Takenaka H, Fujita H, Hanada N, Komohara Y.   +4 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Targeting non-canonical antigens unlocks functional T-cell responses in renal cell carcinoma. [PDF]

J Immunother Cancer
Wang J, Zhu Y, He X, Yin S, He Y, Yao P, Li J, Li X, Shi P, Qian R, Xiao Z, Ye X, Xi JJ, Ye B.   +13 more
europepmc   +1 more source