Results 181 to 190 of about 71,364 (318)

HLA-DR antigens in tuberculoid and lepromatous leprosy

Leprosy Review, 1980
T H, Rea, P I, Terasaki
openaire   +2 more sources

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Tebentafusp (IMCgp100), a first in class immune-mobilizing monoclonal T-cell receptors against cancer (ImmTAC) for HLA-A*02:01 positive uveal melanoma: Product review. [PDF]

Hum Vaccin Immunother
Cohen JE, Mehmi I, Avner M, Moyers J, Hamid O.   +4 more
europepmc   +1 more source

The Gut Microbiome as a Therapeutic Target in Alopecia Areata: Not Yet Part of the Patient Treatment Plan

International Journal of Dermatology, EarlyView.
ABSTRACT Interest in the gut microbiome as a therapeutic target for treating alopecia areata (AA) has grown considerably. However, existing evidence remains limited and inconsistent. Currently, there is insufficient evidence to recommend microbiome‐directed testing and therapies to patients with AA.
Eric McMullen, Deema Abdel Hafeez, Nikhil Pai, Laurence Mainville, Shireen Dumont, Narachai Julanon, Romy Shenderey, Grace Xiong, Shahnawaz Towheed, Jeffrey Donovan   +9 more
wiley   +1 more source

Identification of a shared antigen linking CD4⁺ T and B cell pathology in Sjögren's disease. [PDF]

Sci Adv
Takeshita M, Inamo J, Wakui S, Nagashima R, Nishino T, Tsunoda K, Usuda S, Inokuchi H, Ishigaki K, Sasaki T, Kagoya Y, Suzuki K, Kaneko Y.   +12 more
europepmc   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Use of plasmapheresis during cardiopulmonary bypass in a pediatric heart transplant of a patient with Failing Fontan Physiology: first case in Argentina. [PDF]

J Extra Corpor Technol
Martinez MJ, Berra I, Cornelis J, Costilla J, Zamora F, Delucis PG.   +5 more
europepmc   +1 more source

Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease

Immunology &Cell Biology, EarlyView.
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione, HoChan Cheon, David Vremec, Julika Neumann, Gwenny M Verstappen, Melinda Y Hardy, Mai B Margetts, Lauren J Howson, Lee M Henneken, Maureen Forde, Jason A Tye‐Din, Susanne Heinzel, Philip D Hodgkin, Vanessa L Bryant   +13 more
wiley   +1 more source

The transcriptome of CD14⁺CD163^-HLA-DR^low monocytes predicts mortality in idiopathic pulmonary fibrosis. [PDF]

Eur Respir J
Karampitsakos T, Jia M, Tourki B, Fatima Z, Visinescu B, Perrot CY, Fadli T, Zhao A, Unterman A, Schneider MA, Bandyopadhyay D, Juan-Guardela BM, Vamvakaris I, Prasse A, Noth I, Liggett S, Kreuter M, Drake W, Tzouvelekis A, Garcia JGN, Herzog E, Kaminski N, Benos PV, Herazo-Maya JD.   +23 more
europepmc   +1 more source

Feasibility and outcomes of kidney transplantation in patients with end‐stage kidney disease after haemopoietic stem cell transplantation

Internal Medicine Journal, EarlyView.
Abstract Background Advances in haemopoietic stem cell transplantation (HSCT) have improved long‐term survival, but they have also led to late complications, such as nephropathy. However, the safety and feasibility of kidney transplantation (KT) in patients with HSCT‐related end‐stage kidney disease (ESKD) remain unclear.
Bioh Kim, Seunghyeok Choi, Hanbi Lee, Hye‐Eun Yoon, Hohyung Nam, Silvia Park, Byung Ha Chung   +6 more
wiley   +1 more source