Results 231 to 240 of about 3,066,252 (313)

HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections. [PDF]

Nat Commun
Magyari B, Fülöp AT, Kókai D, Tóth F, Balogh GM, Andreu-Sánchez S, Innocenti G, Weersma RK, Fu J, Pál C, Zhernakova A, Vogl T, Manczinger M.   +12 more
europepmc   +1 more source

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

HLA-E-Directed Accumulation of KIR⁺NKG2C⁺ NK Cells upon HCMV Peptide Presentation In Vitro: Association with the Ex Vivo Phenotype. [PDF]

Int J Mol Sci
Alekseeva NA, Ustiuzhanina MO, Streltsova MA, Vavilova JD, Sapozhnikov AM, Kovalenko EI.   +5 more
europepmc   +1 more source

Clinical Significance of PD‐L1 and HLA Expression in Esophageal Squamous Cell Carcinoma in Response to Immunotherapy

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1507-1517, September 2026.
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu, Yoshiyuki Tagayasu, Yoshihiro Komohara, Cheng Pan, Rin Yamada, Yukio Fujiwara, Kazuto Harada, Keisuke Kosumi, Yoshifumi Baba, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Eradication of pre-clinical prostate tumors by a lentiviral vector-based immunotherapy. [PDF]

Mol Ther Oncol
Vesin B, Fert I, Ciret S, Douguet L, Moncoq F, Noirat A, Authié P, Le Chevalier F, Nevo F, Blanc C, Nemirov K, Majlessi L, Charneau P.   +12 more
europepmc   +1 more source

Evaluation of the Expression and Prognosis of Neural‐Related Products Expressed by Cancer‐Derived Mesenchymal Stem Cells With the Characteristics of Neural Stem Cells

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Studies have demonstrated that the nervous system plays an important role in cancer progression. Nevertheless, the effect of mesenchymal stem cells (MSCs) on cancer has yielded conflicting results. In this study, we discovered that cancer‐derived MSCs (CA‐MSCs) not only exhibit the properties of neural stem cells (NSCs) but also express a ...
Liu Yongjun, Pan Zhiwen, Fu Shangui, Zhai Jinjie, Ying Rongbiao, Chen Zhongjian, Chen Wanyuan, Ju Haixing, Ma Dening, Long Dan, Luo Cong, Fu Zhixuan   +11 more
wiley   +1 more source

Vaccine Therapy for the Management of Penile Cancer: Evidence, Opportunities and Challenges. [PDF]

Vaccines (Basel)
Hatoum F, Nehme R, Fazili A, Miller J, Johnson JS, Le C, Spiess PE, Chahoud J.   +7 more
europepmc   +1 more source

Spatial Omics in High‐Grade Gliomas: Mapping Immune–Tumor Niches for Precision Therapy

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT High‐grade gliomas (HGGs), particularly glioblastoma (GBM), remain among the most lethal human cancers despite decades of molecular profiling and therapeutic innovation. A primary reason for treatment failure is that HGG biology is spatial: malignant cell states, immune suppression, metabolic stress, and therapeutic resistance are organized ...
Saniyah Shaikh, Thaabit Raziq, Sulaf B. Alfares, Touleen T. Raslan, Ismail A. Abdullah, Itika Arora, Shamsa Saleh, Mohammed Imran Khan, Ahmed Yaqinuddin   +8 more
wiley   +1 more source

Mendelian Randomization and Experimental Validation Identify Key Immune Signatures in Bullous Pemphigoid. [PDF]

Clin Cosmet Investig Dermatol
Wang Z, Cui H, Meng L, Yang X, Ye J.
europepmc   +1 more source

Analysis of the Role of N‐Linked Glycans on Human CD1d Molecules

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT CD1d is a cell‐surface expressed glycoprotein that presents a variety of lipid and glycolipid antigens to invariant natural killer T‐cells (iNKT). We have examined the role of the N‐linked glycans on the human CD1d (hCD1d) in modulating the responses of iNKT cells using a combination of cell‐free, cell‐based assays and in silico analyses ...
Syamdas Bandyopadhyay, Sayantan Pradhan
wiley   +1 more source