Results 241 to 250 of about 3,066,252 (313)
Peripheral immune profiling identifies developmental immune displacement into an HLA-DR-low monocyte state in necrotizing enterocolitis. [PDF]
Huang Y +9 more
europepmc +1 more source
ABSTRACT A 64‐year‐old woman presented with seronegative idiopathic granulomatous myositis, featuring severe bulbar weakness, reversible cardiomyopathy (ejection fraction 20%–25%), hepatic injury, and acute kidney injury. Muscle biopsy confirmed granulomatous inflammation.
Balachandran R. Vaidyanathan +2 more
wiley +1 more source
Nomenclature for Factors of the HLA System, 2026. [PDF]
Marsh SGE +14 more
europepmc +1 more source
CCR2/CCR5 Signaling Defines a Pathogenic Interstitial Macrophage Subset That Drives Severe Asthma
In mouse model of severe asthma, protective resident alveolar macrophages are depleted and replaced by monocyte‐derived populations, particularly a Lyve1loMHCIIhi interstitial macrophage subset enriched for Ccr2/Ccr5 and inflammatory gene programs. Blocking this subset with a dual CCR2/CCR5 antagonist reduces airway inflammation, restores homeostasis ...
Hao Wang +8 more
wiley +1 more source
Sepsis-related immunosuppression: a comprehensive review of current research breakthroughs. [PDF]
Ren S, Wen J.
europepmc +1 more source
Abstract Objectives Despite their anti‐cancer properties, natural killer (NK) cells are discarded during CAR T cell manufacturing. NK cells display promising responses as a cell therapy, exhibiting remarkable safety at high doses. Moreover, NK cells have complementary cytokine profiles and distinct antigen‐recognition pathways to supplement CAR T cell ...
Lachlan J Dobson +7 more
wiley +1 more source
An Immunoinformatic Approach for a Multi-Epitope Vaccine Against Toxoplasma gondii. [PDF]
Asadi N +7 more
europepmc +1 more source
SARS‐CoV‐2 infection drives transient B‐cell remodeling toward an activated, regulatory‐like phenotype. In this randomized sub‐study, the polyclonal neutralizing antibody XAV‐19 did not detectably alter B‐cell phenotype, transcriptome, or function relative to placebo, indicating that passive polyclonal therapy preserves B‐cell homeostasis during acute ...
Nicolas Degauque +19 more
wiley +1 more source
IL-15/NKG2D signaling-mediated activation of CD8<sup>+</sup> T cell bypass pathways in sepsis-induced immune injury. [PDF]
Wang S, Liu L, Mao R, Liu Y, Chai Y.
europepmc +1 more source

