Results 151 to 160 of about 183,897 (254)

Speckle Observations With PISCO in Calern (France): III. Astrometric Measurements of Visual Double Stars in 2019 and New or Revised Orbits for STT531 AB, STT77 AB, STF1338 AB, COU1746, STT260, A1109 AB, HU1291, and A632 AB

Astronomische Nachrichten, EarlyView.
ABSTRACT We present relative astrometric measurements of visual double stars, made in 2019 with the speckle camera PISCO at the 1‐m Epsilon telescope of the C2PU facility (Observatoire de la Côte d'Azur, Calern site). Our observing list contains orbital couples as well as double stars whose motion is still uncertain.
J.‐L. Prieur, M. Scardia, J.‐P. Rivet, E. Aristidi, J. F. Ling, L. Piccotti, L. Pansecchi, R. W. Argyle, L. Abe, P. Bendjoya, L. Maccarini, D. Vernet   +11 more
wiley   +1 more source

HLA-E: Immune Receptor Functional Mechanisms Revealed by Structural Studies. [PDF]

Immunol Rev
Gillespie GM, Quastel MN, McMichael AJ.
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Hantaan virus-derived peptides that stabilize HLA-E could abrogate inhibition of CD56dimNKG2A+ NK cells. [PDF]

PLoS Pathog
Xue M, Tang K, Zhang Y, Xu X, Zhang C, Zuo J, Wang F, Zhang X, Zheng X, Zhuang R, Zhang Y, Jin B, Ma Y.   +12 more
europepmc   +1 more source

Emerging roles of natural killer cell ligands-HLA-E, HLA-F, HLA-G, MICA, and MICB-in <i>in vitro</i> fertilization outcomes. [PDF]

Front Genet
Chaaithanya IK, Rajalingam R.
europepmc   +1 more source

Cytotoxic Lymphocyte Recognition of HLA-E [PDF]

Immunity, 1998
openaire   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

The Novel HLA-E*01:152 Allele Identified in African Populations Using Next-Generation Sequencing. [PDF]

HLA
Naidoo N, Ng'uni TL, Padia U, Banjoko AW, Ndhlovu ZM.   +4 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source