Results 191 to 200 of about 84,983 (267)

Multiparameter antigen-specific immunoprofiling in subjects with negative IGRA and TST results with potential <i>M. tuberculosis</i> exposures. [PDF]

Front Cell Infect Microbiol
Pathakumari B, Gutierrez LE, Faisal SA, Sanchez PA, Daniel K, Van Keulen VP, Hilgart HR, Reddy MR, Theel E, Laniado-Laborin R, Clain JM, Peikert T, Bailey RC, Escalante P.   +13 more
europepmc   +1 more source

Synaptotagmin 1 and Synaptotagmin 7 promote MR1-mediated presentation of <i>Mycobacterium tuberculosis</i> antigens. [PDF]

Elife
Kim SJ, Peterson JC, Olive AJ, Tafesse FG, Kulicke CA, Karamooz E, Lewinsohn D.   +6 more
europepmc   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

A Platform for High-throughput and Ultrasensitive Immunopeptidomics. [PDF]

Mol Cell Proteomics
Gul A, Van Moortel L, Willems P, Aernout I, Pedró-Cos L, Ferrell KC, Boucher K, Staes A, Devos S, Lentacker I, Vandekerckhove B, Demangel C, Thery F, Impens F.   +13 more
europepmc   +1 more source

Granzyme K: A new frontier in systemic lupus erythematosus

Rheumatology &Autoimmunity, EarlyView.
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen, Yunjing Pu, Peihui Yang, Qinghuan Zhu, Haojun Long, Danqi Deng   +5 more
wiley   +1 more source

Computational design and molecular characterization of a multi-epitope peptide vaccine targeting pancreatic cancer. [PDF]

J Genet Eng Biotechnol
Rahimi SM, Nouri HR.
europepmc   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Human Leukocyte Antigen (HLA) and Tumor Immunity: A Critical Link in Cancer Immunotherapy. [PDF]

Immun Inflamm Dis
Damian D.
europepmc   +1 more source

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

HLA-DR risk variants in rheumatoid arthritis: what we know and still do not know. [PDF]

RMD Open
Yap CF, Viatte S.
europepmc   +1 more source