Results 151 to 160 of about 171,039 (261)

Characterization of NAT2 Using Long‐Read Sequencing: Allele, Diplotype, and Phenotype Call Accuracy Compared to Other Testing Strategies

Clinical Pharmacology &Therapeutics, EarlyView.
The NAT2 pharmacogene is essential in drug metabolism, particularly for aromatic amines and hydrazines. Genetic variations in NAT2 categorize individuals as rapid, intermediate, or poor metabolizers based on their acetylation capacity to inform dosing guidelines.
Shobana John, Erin C. Boone, Byunggil Yoo, Laura B. Ramsey, Andrea Gaedigk   +4 more
wiley   +1 more source

Immune dysregulation in endometrial tuberculosis: elevated HLA-G and IL-1Ra as key modulators. [PDF]

Front Cell Infect Microbiol
Huang D, Dai J, Yu H, Chen W.
europepmc   +1 more source

CytoScan: Automated Detection of Technical Anomalies for Cytometry Quality Control

Cytometry Part A, EarlyView.
ABSTRACT Studies evaluating cellular phenotypes by cytometry techniques are increasingly facing analytical challenges due to the multitudes of samples and parameters that are evaluated concurrently. Spurious technical effects resulting from a lack of standardization can affect marker distributions and further complicate multi‐sample analyses.
Tim R. Mocking, Felix Zwolle, Yejin Park, Angèle Kelder, Yvan Saeys, Jacqueline Cloos, Sofie van Gassen, Costa Bachas   +7 more
wiley   +1 more source

HLA-G 14 bp polymorphism: Implications and its associated risk to malaria severity among iron-fortified Ghanaian infants and young children. [PDF]

PLoS One
Tetteh Danquah A, Courtin D, Asamoah Sakyi S, Nakotey GK, Tchum SK, Afriyie Duah N, Lagrave A, Sewor C, Amoani B.   +8 more
europepmc   +1 more source

FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1485-1489, April 2025.
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Sanjay Divakaran, Vinay Randhawa, Usman A. Tahir, Matthew Robertson, Anam A. Waheed, Anna Perillo, Leanne Barrett, Ron Blankstein, Mark W. Feinberg, Marcelo F. Di Carli, Neal K. Lakdawala   +10 more
wiley   +1 more source

JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G. [PDF]

iScience
Obermajer N, Zwolak A, van de Ven K, Versmissen S, Menard K, Rogers K, Petley T, Weinstock D, Aligo J, Patel J, Tian K, Angelillo L, Yi F, Jarantow S, Schutsky K, Hamuro Y, Arias DA, Buyens K, Sheena Yao TW, Torti V, Brajic A, Geist B, van Heerden M, Chu G, Verbist B, Ongenaert M, Häsler J, Packman K, Shenton J, Lenox L, Clawson J, Brown RJ, Lauring J, Greger JG, Brehmer D, Singh S, Lorenzi MV, Laquerre S.   +37 more
europepmc   +1 more source

HLA-G high-expressor 3'UTR markers are linked to gastric cancer development and survival. [PDF]

Cancer Immunol Immunother
Vaquero-Yuste C, Juarez I, Molina-Alejandre M, Molanes-López EM, Gutiérrez-Calvo A, López-García A, Lasa I, Gómez R, Arnaiz-Villena A, Martín-Villa JM.   +9 more
europepmc   +1 more source

The implication of serum HLA-G in angiogenesis of multiple myeloma. [PDF]

Mol Med
Wang C, Su NW, Hsu K, Kao CW, Chang MC, Chang YF, Lim KH, Chiang YH, Chang YC, Sung MT, Wu HH, Chen CG.   +11 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Bone marrow-derived extracellular vesicles from multiple myeloma patients promote adaptive immune dysfunction via HLA-G, PD-1, and PD-L1. [PDF]

Front Immunol
Soncini D, Marimpietri D, Ladisa F, Lai F, Airoldi I, Gramignoli R, Cea M, Morandi F.   +7 more
europepmc   +1 more source