Results 1 to 10 of about 106,774 (312)

Antigens HLA-G, sHLA- G and sHLA- class I in reproductive failure.

open access: yesFolia Histochemica et Cytobiologica, 2008
It can be supposed that relation between HLA-G polymorphism and sHLA-G protein expression are associated with successful embryo implantation and pregnancy maintenance.
Elzbieta Ronin-Walknowska   +4 more
doaj   +7 more sources

Role of HLA-G in Viral Infections

open access: yesFrontiers in Immunology, 2022
The human leukocyte antigen (HLA)-G is a non-classical HLA class I molecule, which has distinct features to classical HLA-A, -B, -C antigens, such as a low polymorphism, different splice variants, highly restricted, tightly regulated expression and ...
Simon Jasinski-Bergner   +4 more
doaj   +1 more source

Histological Characterization of Class I HLA Molecules in Whole Umbilical Cord Tissue Towards an Inexhaustible Graft Alternative for Reconstructive Surgery

open access: yesBioengineering, 2023
Background: Limited graft availability is a constant clinical concern. Hence, the umbilical cord (UC) is an attractive alternative to autologous grafts.
Yue Ying Yao   +7 more
doaj   +1 more source

Effect of HLA-G5 Immune Checkpoint Molecule on the Expression of ILT-2, CD27, and CD38 in Splenic B cells

open access: yesJournal of Immunology Research, 2022
The human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with a complex network of interactions with several inhibitory receptors. Although the effect of HLA-G on T cells and NK cells is well studied, the effect of HLA-G on B cells is still
Hana Rohn   +8 more
doaj   +1 more source

Serum levels of soluble HLA-G correlate with disease activity in pediatric patients with Crohn's disease

open access: yesThe Saudi Journal of Gastroenterology, 2022
Background: Human leukocyte antigen (HLA)-G, a member of the HLA family, is crucial for fetomaternal tolerance. Transmembrane or circulating/soluble HLA-G (sHLA-G) is elevated in autoimmune conditions and the tumor microenvironment.
Murat Cansever   +3 more
doaj   +1 more source

The HLA Ligandome Comprises a Limited Repertoire of O-GlcNAcylated Antigens Preferentially Associated With HLA-B*07:02

open access: yesFrontiers in Immunology, 2021
Mass-spectrometry based immunopeptidomics has provided unprecedented insights into antigen presentation, not only charting an enormous ligandome of self-antigens, but also cancer neoantigens and peptide antigens harbouring post-translational ...
Soumya Mukherjee   +9 more
doaj   +1 more source

Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases

open access: yesBiomolecules, 2022
Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with immune-regulatory properties in cancers and infectious diseases, presents both membrane-bound and soluble (sHLA-G) isoforms.
Sajad Rashidi   +7 more
doaj   +1 more source

Expression and potential roles of HLA-G in human spermatogenesis and early embryonic development. [PDF]

open access: yesPLoS ONE, 2014
As one of the non-classical major histocompatibility complex(MHC)-1 antigens, Human Leukocyte Antigen G (HLA-G), has been suggested as a prognostic marker to identify the embryo developmental potential. In the present study, we investigated the potential
Gui-Dong Yao   +6 more
doaj   +1 more source

B Cells Control Mucosal-Associated Invariant T Cell Responses to Salmonella enterica Serovar Typhi Infection Through the CD85j HLA-G Receptor

open access: yesFrontiers in Immunology, 2021
Mucosal-associated invariant T (MAIT) cells are an innate-like population of T cells that display a TCR Vα7.2+ CD161+ phenotype and are restricted by the nonclassical MHC-related molecule 1 (MR1).
Rosângela Salerno-Gonçalves   +5 more
doaj   +1 more source

HUMAN LEUKOCYTE ANTIGEN (HLA)-G: AS AN INVISIBILITY CLOAK FOR TUMOR CELLS IN HEMATOLOGICAL MALIGNANCIES

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: Hematological malignancies are a disease group that affects blood cells derived from myeloid or lymphoid lineage, resulting in impaired hematopoiesis. These neoplasms include mainly leukemias, lymphomas and multiple myeloma (MM).
TLP Ribeiro   +7 more
doaj   +1 more source

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