Results 191 to 200 of about 106,774 (312)

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Role of Donor Unrestricted T Cells (DURTs) in TB Host Defense: Implications for Novel TB Vaccine Development. [PDF]

Vaccines (Basel)
Kain D, Lewinsohn DM, Lewinsohn DA.
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Pleiotropic effects of BET inhibition broadly boost tumor immunogenicity to CD8^<b>+</b> T cells. [PDF]

Oncoimmunology
Melief J, Baldran-Groves L, Gerault MA, Liang YY, Pasca S, de Los Santos MC, Wickström S, Lövgren T, Ramos AD, Larsson LG, Nordlund P, Seliger B, Kiessling R.   +12 more
europepmc   +1 more source

HLA-J, A SECOND INACTIVATED CLASS I HLA GENE RELATED TO HLA-G AND HLA-A [PDF]

, 1992
Zemmour, Jaqueline, Messer, Gerald, Girdlestone, J., Orr, Harry T., Weiss, Elisabeth H., Parham, P.   +5 more
core   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Epstein-Barr virus-associated multiple sclerosis: recent mechanistic advances and clinical therapeutic perspectives. [PDF]

Front Immunol
Cheng R, Gao Y, Zheng R, Wen M, Li G, Pan W, Liao Y, Wen L, Hu Y, Zhao-Fleming H, Shang P.   +10 more
europepmc   +1 more source

bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers

iMetaMed, EarlyView.
We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang, Li Yuan, Katie W. Gu, Xiangdong Cheng, Bo Wen, Zhao Zhang   +5 more
wiley   +1 more source

GENETIC POLYMORPHISMS OF HLA-G ANTIGEN IN IRAQI WOMEN WITH UNEXPLAINED RECURRENT MISCARRIAGE.

International Journal of Advanced Research, 2016
Reema M.Abd, HasanF Al-Azzawie, Kareem Al-Kazzaz.   +2 more
openaire   +1 more source

Engineering TCR-directed T-cells for the treatment of multiple myeloma. [PDF]

Front Immunol
Mubin N, Ignatz-Hoover JJ, Driscoll JJ.
europepmc   +1 more source