Results 101 to 110 of about 401,649 (316)
Revista Alergia México, 2018 Antecedentes: Todavía se desconoce el origen del poblamiento americano, pero con el tiempo se han desarrollado diversas teorías al respecto. Colombia fue un importante vínculo entre los hemisferios Norte y el Sur del continente americano.
Carlos Hernando-Parga
doaj
The HLA-C*14:152 Allele Was Identified Using a Next-Generation Sequencing Method
HLA-C*14:152 differs from HLA-C*14:02:01:01 by a non-synonymous nucleotide substitution in exon ...
John Jeongseok Yang +2 more
core +1 more source
Advanced Science, EarlyView.This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng +7 more
wiley +1 more source
Annual Review of Immunology, 2015 Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown. Two broad theories most likely explain the role of HLA-B27 in AS pathogenesis. The first is based on the natural immunological function of HLA-B27 of presenting
openaire +2 more sources
CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells
Advanced Science, EarlyView.AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu +6 more
wiley +1 more source
Genomic full-length sequence of the novel HLA-B*40:540N allele
The coding sequence of HLA-B*40:540N differs from HLA-B*40:02:01:01 by a non-synonymous nucleotide substitution in exon ...
John Jeongseok Yang, Heung-Bum Oh
core +1 more source
Summary of free HLA, free TCR and the various p-HLA and p-HLA-TCR complexes during MD trajectories.
, 2016 Summary of free HLA, free TCR and the various p-HLA and p-HLA-TCR complexes during MD trajectories.
José Antonio Pérez-Simón (510830) +5 more
core +1 more source
Advanced Science, EarlyView.Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana +19 more
wiley +1 more source
Inmunogenética e inmunopatología de la diabetes insulinodependiente tipo I
Salud Uninorte, 2005 La diabetes insulinodependiente tipo I (T1D) es una enfermedad crónica y autoinmune que altera la calidad de vida en niños desde muy temprana edad. Esta patología genera un alto costo para la salud pública y produce trastornos psicoafectivos en el ...
Gloria Garavito +4 more
doaj
Clinical, biochemical and genetic characteristics of familial forms of type 1 diabetes
Сахарный диабетBACKGROUND: Familial clustering of type 1 diabetes (T1D) highlights the importance of genetic and environmental factors in the pathophysiology of diabetes mellitus (DM).
I. M. Zufarova +7 more
doaj +1 more source