Results 81 to 90 of about 401,649 (316)

Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis

, 2004
In order to analyze whether loci in the human leukocyte antigen (HLA) class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis (MS), we examined selected microsatellite markers in 177 Nordic sib-pair ...
K.-M. Myhr, Fredrikson, S, A. Spurkland, Celius, EG, Dai, KZ, L.P. Ryder, E.G. Celius, Mellgren, SI, F. Vartdal, K.-Z. Dai, Lorentzen, AR, M. Laaksonen, Vartdal, F, H.F. Harbo, A. Svejgaard, A. Edland, Andersen, O, J. Hillert, Nyland, H, A. Compston, S. Fredrikson, Hillert, J, P.S. Sorensen, H. Nyland, Sawcer, S, Spurkland, A, Edland, A, Oturai, A, B.A. Lie, O. Andersen, A.R. Lorentzen, Lie, BA, S. Sawcer, Myhr, KM, Sorensen, PS, M. Sandberg-Wollheim, S.I. Mellgren, Laaksonen, M, Compston, A, Harbo, HF, A. Oturai, Svejgaard, A, Ryder, LP, Lorentzen, Å, Hillert, J,, Sandberg Wollheim, Magnhild,, Lund University.   +46 more
core   +1 more source

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]

, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy, Battegay, Manuel, E. Freitas, Jeffrey, G., James, Ian, Park, Lawrence P, Swiss HIV Cohort Study,, G. Jeffrey, Battegay, M., Jeffrey, Gary, Weber, R., Chapman, R., S. Herrmann, Furrer, Hansjakob, Telenti, Amalio, Telenti, A., Lucas, M., M. Lucas, null null, I. James, Weber, Rainer, Freitas, Elizabeth, H. Furrer, Gaudieri, S., S. A. Mallal, Park, P., Freitas, E., Cheng, W., K. Pfafferott, S. Gaudieri, R. Weber, Naidoo, Kiloshni, A. Rauch, Pfafferott, K., Mallal, Simon A, L. P. Park, Rauch, A., A. Telenti, Pfafferott, Katja, R. Chapman, Lucas, Michaela, M. Battegay, Park, L.P., Herrmann, Susan, K. Naidoo, Furrer, H., Rauch, Andri, W. Cheng, Herrmann, S., Naidoo, K., Chapman, Russell, Mallal, S.A., James, I., Gaudieri, Silvana, Park, Lawrence P., Mallal, S. A., Mallal, Simon A., Park, L. P.   +57 more
core   +1 more source

Identification of the novel HLA-DQA1*01:03:07 allele using next-generation sequencing

, 2023
The HLA-DQA1*01:03:07 allele differs from HLA-DQA1*01:03:01:01 allele by a single nucleotide in codon -8 ...
박윤희
core   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

The HLA-B*58:01:43 allele identified in a Korean individual awaiting hematopoietic stem cell transplant

HLA-B*58:01:43 differs from HLA-B*58:01:01:01 by one synonymous nucleotide substitution in codon ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

[Translated article] Letter to the Editor of RECOT. “Functional outcomes and eight-year survival of hip arthroscopy in patients with degenerative hip disease” by D. Torres-Perez et al

Revista Española de Cirugía Ortopédica y Traumatología, 2022
J. Sanz-Reig, J. Más-Martínez
doaj   +1 more source

HLA Typing in Iraqi Patients with Obesity and Primary Osteoarthritis.

مجله كليه طب الكندي, 2013
Background: Osteoarthritis (OA) is a degenerative joint disease. It is one of the major causes of disability in developed and developing countries. Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.Objectives: To ...
Sadiq Abbas Al-Mukhtar, Faris Abdul-Kareem, Haider Hashim Zalzala, Batool Mutar Mahdi, Hyam Raouf, Laheeb Ali Abid, Zena Nehad   +6 more
doaj  

HLA DRB1* ASSOCIATION WITH REPRODUCTIVE DISORDERS IN WOMEN

Медицинская иммунология, 2014
. HLA DRB1* gene associations with idiopathic fetal losses and infertility were studied in women. It was shown that idiopathic fetal losses are associated with HLA DRB1*04 specificity, whereas infertility correlated with HLA DRB1*04/07 genotype.
L. A. Gordeeva, A. V. Shabaldin, A. N. Glushkov, O. A. Glushkova, O. S. Makarchenko, T. A. Simonova, I. V. Vetrova, E. A. Sherina, N. K. Zhilinskaya, V. I. Minina   +9 more
doaj   +1 more source

Genomic full-length sequence of the novel HLA-B*56:94 allele

HLA-B*56:94 differs from HLA-B*56:05:01 by two non-synonymous nucleotide substitutions in exon 1 and synonymous nucleotide substitutions in exon 1 and exon ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source