Graphical abstract illustrating the study design, experimental workflow, and key findings from single‐cell profiling of peripheral mononuclear cells in multiple sclerosis patients undergoing anti‐CD20 therapy, revealing disease‐ and treatment‐associated immune signatures.
Mie Waede+10 more
wiley +1 more source
The HLA system and the arthropathies associated with psoriasis.
C J Eastmond, J. C. Woodrow
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Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich+20 more
wiley +1 more source
Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville+6 more
wiley +1 more source
Lack of immunogenicity for an influenza-derived peptide across the HLA-B44 supertype molecules. [PDF]
Leong SL+3 more
europepmc +1 more source
Both chains of HLA-DR bind to the membrane with a penultimate hydrophobic region and the heavy chain is phosphorylated at its hydrophilic carboxyl terminus. [PDF]
Jim Kaufman, Jack L. Strominger
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Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai+5 more
wiley +1 more source
Regulation of major histocompatibility complex class-I (MHC-I) gene methylation using DNA methyltransferase inhibitor and PD-L1 inhibitor in triple negative breast cancer. [PDF]
Jeong YJ, Lee NR, Oh HK.
europepmc +1 more source
Failure of lymphocyte-membrane HLA-A and -B expression in two siblings with combined immunodeficiency [PDF]
Ruud K. B. Schuurman+7 more
openalex +1 more source