Results 71 to 80 of about 589,195 (286)

Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease [PDF]

, 1992
Autoimmune chronic active liver disease (ACALD), a major indication for liver transplantation, is associated strongly with antigenic determinants HLA-B8 and DR3.
Block, GD, Bou-Abboud, CF, Demetris, AJ, Hassanein, T, Starzl, TE, Van Thiel, DH, Wright, HL   +6 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A generic RNA pulsed DC based approach for developing therapeutic intervention against nasopharyngeal carcinoma

Human Vaccines & Immunotherapeutics, 2017
The recurrent nasopharyngeal carcinoma of head-and-neck cancers pathology showed unique symptoms and clinical characteristics. The complexity of pathology poses challenges for developing therapeutic interventional approaches against nasopharyngeal ...
Rajeev K. Tyagi, Rajesh Parmar, Naisargee Patel   +2 more
doaj   +1 more source

SIGNIFICANCE OF IMMUNOGENETIC PREDISPOSAL FOR CLINICAL COURSE OF MYASTHENIA

Медицинская иммунология, 2014
. The aim of this work was to reveal novel criteria for prediction of clinical course in myasthenia, based on immunogenetic characteristics of the patients.
L. N. Bubnova, I. E. Pavlova, V. V. Baranov, N. M. Zhulev   +3 more
doaj   +1 more source

Simple models of the chemical field around swimming plankton [PDF]

, 2010
Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection.
Bao, Xiao,, Brown, Matthew A.,, Castro, Felipe,, Cortes, Adrian,, Coutlée, François,, Cremin, Katie,, Cruickshank, Maggie,, Duncan, Emma L.,, Franco, Eduardo L.,, Frazer, Ian H.,, Garland, Suzanne M.,, Hanson, Aimee L.,, Hemminki, Kari,, Hildesheim, Allan,, Johnson, Lisa G.,, Leo, Paul J.,, Little, Julian,, Lund University., Lund University., Madeleine, Margaret M.,, Marshall, Mhairi,, Mukhopadhyay, Pamela,, Newell, Felicity,, Ohlsson, Claes,, Pettersson-Kymmer, Ulrika,, Rader, Janet S.,, Safaeian, Mahboobeh,, Schwartz, Stephen M.,, Sitas, Freddy,, Steinberg, Winfried,, Sun, Ying Pu,, Tabrizi, Sepehr N.,, Tiews, Sven,, Trimble, Cornelia,, Wang, Sophia S.,, Wentzensen, Nicolas,   +35 more
core   +2 more sources

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

Arthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Y. Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source

HLA-A, HLA-B and HLA-C Polymorphism in the Slovak Population

Folia Biologica, 2000
The occurrence rates of class I HLA alleles were investigated in a sample of the Slovak population by a PCR-SSP method. The frequencies of HLA-A alleles ranged from 0.00 for A*4301 to 0.2798 for A*0201-22; the frequencies of HLA-B alleles ranged from 0.00 for B*4601, B*4801-3, B*5901, B*7301, and B*8101 to 0.1101 for B*4402-10, and those of HLA-C ...
E, Kulcsárová, M, Buc, S, Ferencik
openaire   +2 more sources

Association of HLA-C*07:359 with HLA-A, -B, and -DRB1 alleles in Taiwanese

Tzu Chi Medical Journal
Objectives: It is thought that Taiwanese indigenous people were the “first people” to populate Taiwan (Formosa) having been there for over 5000 years, preceding the Dutch colonization (from 1624 to 1662) and Spanish colonization (from 1626 to 1642 ...
Kuo-Liang Yang, Py-Yu Lin
doaj   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source