Results 11 to 20 of about 1,234,411 (332)

Differences in Immunogenicity of HLA Antigens and the Impact of Cross-Reactivity on the Humoral Response

Transplantation, 2014
Background Information about differences in immunogenicity of various HLA antigens may help guide donor selection and identify mismatches to avoid for patients likely to need retransplantation.
D. Lucas, M. Leffell, A. Zachary
semanticscholar   +1 more source

Antibodies reactive to non-HLA antigens in transplant glomerulopathy.

Journal of the American Society of Nephrology, 2011
Although T and B cell alloimmunity contribute to transplant injury, autoimmunity directed at kidney-expressed, non-HLA antigens may also participate. Because the specificity, prevalence, and importance of antibodies to non-HLA antigens in late allograft ...
R. Dinavahi, Ajish George, Anne Tretin, E. Akalin, S. Ames, J. Bromberg, G. Deboccardo, N. Dipaola, S. Lerner, A. Mehrotra, B. Murphy, T. Nadasdy, E. Paz-Artal, D. Salomon, B. Schröppel, V. Sehgal, R. Sachidanandam, P. Heeger   +17 more
semanticscholar   +1 more source

HLA antigens and uveitis. [PDF]

British Journal of Ophthalmology, 1977
We have studied the antigen frequencies in a group of adult patients with acute and chronic iridocyclitis and chronic, cyclitis. In patients with iridocyclitis a statistically significant increased incidence of HLA-B27 was noted, even in those patients without joint or systemic disease.
G. R. O'Connor, S. J. Kimura, S. Ohno, D. H. Char   +3 more
openaire   +3 more sources

Role for intracellular proteases in the processing and transport of class II HLA antigens.

Proceedings of the National Academy of Sciences of the United States of America, 1988
Human B-lymphoblastoid cell lines (B-LCL) incubated with the protease inhibitor leupeptin accumulate complexes of class II HLA antigens with a series of Mr 21,000-23,000 basic proteins termed leupeptin-induced proteins (LIP).
J. Blum, P. Cresswell
semanticscholar   +1 more source

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens

Frontiers in Immunology, 2020
Patients undergoing allogeneic stem cell transplantation as treatment for hematological diseases face the risk of Graft-versus-Host Disease as well as relapse. Graft-versus-Host Disease and the favorable Graft-versus-Leukemia effect are mediated by donor
Kyra J. Fuchs, M. Willy Honders, Edith D. van der Meijden, Edith D. van der Meijden, Alwin E. Adriaans, Dyantha I. van der Lee, Margot J. Pont, Margot J. Pont, Ramin Monajemi, Szymon M. Kielbasa, Peter A. C. ’t Hoen, Peter A. C. ’t Hoen, Cornelis A. M. van Bergen, J. H. Frederik Falkenburg, Marieke Griffioen   +14 more
doaj   +1 more source

Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations.

Proceedings of the National Academy of Sciences of the United States of America, 1976
Amino-acid and carbohydrate compositions in addition to limited NH2-terminal sequence data of four preparations of HLA antigens, including products of both of the major histocompatibility loci (HLA-A and HLA-B), show that the antigens have great homology
C. Terhorst, P. Parham, D. Mann, J. Strominger   +3 more
semanticscholar   +1 more source

Comprehensive analysis of mycobacterium tuberculosis antigen-specific CD4+ T cell responses restricted by single HLA class II allotype in an individual

Frontiers in Immunology, 2022
Mycobacterium tuberculosis infection is generally asymptomatic as latent tuberculosis, but it is still known as the world’s leading bacterial cause of death.
Yong-Hun Lee, Yong-Hun Lee, You-Seok Hyun, You-Seok Hyun, Hyeong-A Jo, Hyeong-A Jo, In-Cheol Baek, Sun-Mi Kim, Hyun-Jung Sohn, Tai-Gyu Kim, Tai-Gyu Kim, Tai-Gyu Kim   +11 more
doaj   +1 more source

Enhanced expression of beta2-microglobulin and HLA antigens on human lymphoid cells by interferon.

Proceedings of the National Academy of Sciences of the United States of America, 1978
Mononuclear cells from the blood of healthy normal humans were kept in cultures under nonstimulating conditions for 16 hr in the presence or absence of human interferon.
I. Heron, M. Hokland, K. Berg
semanticscholar   +1 more source

Peculiarities of phenotypes of patients with pyelo- and glomerulonephritis by HLA distribution analysis

Український Журнал Нефрології та Діалізу, 2018
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis of chronic kidney disease (CKD) have demonstrated the associative links of the HLA antigens, which stipulate the relative and attributive risks of some autoimmune diseases ...
V. Driianska, O. Petrina, M. Velychko, F. Haisenyuk, G. Drannik   +4 more
doaj   +1 more source

HLA Epitopes: The Targets of Monoclonal and Alloantibodies Defined

Journal of Immunology Research, 2017
Sensitization to human leukocyte antigens (HLA) in organ transplant patients causes graft rejection, according to the humoral theory of transplantation. Sensitization is almost ubiquitous as anti-HLA antibodies are found in almost all sera of transplant ...
Nadim El-Awar, Vadim Jucaud, Anh Nguyen
doaj   +1 more source