Results 191 to 200 of about 111,549 (295)

Distinct effects of adjuvants on B cell responses to protein or polysaccharide antigens contained in glycoconjugate vaccines. [PDF]

Front Immunol
Budroni S, Faenzi E, Tavarini S, Sammicheli C, Buricchi F, Volpini G, Borgogni E, Spensieri F, Balducci E, Galletti B, Romano MR, D'Oro U, Finco O, Bardelli M.   +13 more
europepmc   +1 more source

Trypsin inihibitors inhibit induction by interferon-γ of HLA-DR antigen expression on human skin cells

, 1989
Brian D. Berman, Bonnie Smith
openalex   +1 more source

HLA class II antigens (DR, DQ loci) and peripheral arthritis in ankylosing spondylitis. [PDF]

, 1987
Raimón Sanmartí, M.G. Ercilla, M A Brancós, María C. Cid, A. Collado, J Rotès-Quérol   +5 more
openalex   +1 more source

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

Glia, EarlyView.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli, Insa Hirschberg, Christin Weissleder, Carmela Giachino, María José Pérez, Malvina Dubroux, Francesca Provenzano, Mafalda Rizzuti, Linda Ottoboni, Udit Sheth, Tania F. Gendron, Stefania Corti, Michela Deleidi   +12 more
wiley   +1 more source

Isolation and identification of a cDNA clone corresponding to an HLA-DR antigen beta chain. [PDF]

, 1982
Klas G. Wiman, Dan Larhammar, Lena Claesson, Kenth Gustafsson, L. Schenning, P. Bill, Jan Böhme, Maurizio Denaro, B Dobberstein, Ulf Hammerling, Sune Kvist, B Servenius, Johan Sundelin, P A Peterson, Lars Rask   +14 more
openalex   +1 more source

A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease. [PDF]

JCI Insight
Yang FC, Besser HA, Chun HR, Albertelli M, Fernandez-Becker NQ, Jabri B, Khosla C.   +6 more
europepmc   +1 more source

Human histocompatibility antigen mutants immunoselected in vitro. Biochemical analysis of a mutant which synthesizes an altered HLA-A2 heavy chain.

, 1982
Michael S. Krangel, Donald Pious, Jack L. Strominger   +2 more
openalex   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source