UpTCR: a unified progressive knowledge transfer foundation model for robust T-cell receptor-antigen binding recognition. [PDF]
Lv T +24 more
europepmc +1 more source
The HLA Antigen and Leprosy in Korea
Se Jong Kim, In Hong Choi, Joo Deuk Kim
openaire +2 more sources
Abstract Purpose To systematically review randomized controlled trials and quantitatively evaluate the efficacy and safety of injections of autologous adipose‐derived mesenchymal stromal cells (AD‐MSCs) in patients with knee osteoarthritis (OA). Methods Multiple electronic databases were searched with no date restrictions for randomized controlled ...
Joo Hyung Han +8 more
wiley +1 more source
The Antigen-Presentation Bottleneck in Pediatric Solid Tumors: Developmental Antigens, MHC-I Suppression, and Therapeutic Restoration of Tumor Immune Recognition. [PDF]
Alghoul WII +6 more
europepmc +1 more source
Host-driven citrullination of extracellular vesicle-derived microbial proteins links <i>P</i> <i>orphyromonas gingivalis</i> to rheumatoid arthritis. [PDF]
Cheng X, Gong W.
europepmc +1 more source
Proteomic and proteogenomic identification of targetable T-cell antigens in multiple myeloma. [PDF]
Zuleger G +22 more
europepmc +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Non-HLA Antibodies in Kidney Transplantation: Mediators of Allograft Injury or Markers of Dysregulated Humoral Immunity? [PDF]
Fouza A, Daoudaki M.
europepmc +1 more source
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang +4 more
wiley +1 more source
Organoid Coculture Models for Cancer Research and Immunotherapy
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source

