Results 191 to 200 of about 191,208 (362)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Engineering TCR-directed T-cells for the treatment of multiple myeloma. [PDF]

Front Immunol
Mubin N, Ignatz-Hoover JJ, Driscoll JJ.
europepmc   +1 more source

About HLA antigen epitopes (2) : Overview of Serological HLA Typing

Miyuki Uchida, Hidenori Tanaka
openalex   +2 more sources

Determination of unacceptable antigens by summation of anti-HLA eplet antibody strength (MFI) based on single antigen bead assays: Excellent correlation with negative cell based cross matches

, 2022
Allen J. Norin, Ballabh Das, Mary O. Mondragon-Escorpizo, Harsha Bajaj, Nabil Sumrani, Devon John, Moro O. Salifu   +6 more
openalex   +1 more source

Tolerability and efficacy of chemosaturation in combination with systemic therapy for metastatic uveal melanoma

International Journal of Cancer, EarlyView.
What's New? Uveal melanoma is the most common primary intraocular cancer in adults, and up to half of patients develop metastatic disease, predominantly in the liver, where prognosis remains poor despite promising treatment options. In this study, the authors evaluated the safety and efficacy of administering systemic therapy within 40 days of liver ...
Patrick Kasteleiner, Gerd Grözinger, Jörg Schmehl, Lukas Flatz, Andrea Forschner   +4 more
wiley   +1 more source

Identification and prioritisation of tumour antigen candidates from 79 glioblastoma transcriptomes. [PDF]

Cancer Immunol Immunother
Kert Š, Pižem J, Petrin S, Bošnjak M, Jerala M, Matjašič A, Zupan A.   +6 more
europepmc   +1 more source

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

, 2013
Paul J. Norman, Jill A. Hollenbach, Neda Nemat‐Gorgani, Lisbeth A. Guethlein, Hugo G. Hilton, Marcelo J. Pando, Kwadwo Koram, Eleanor M. Riley, Laurent Abi-Rached, Peter Parham   +9 more
openalex   +2 more sources

Sirolimus with CSP and MMF as GVHD prophylaxis for allogeneic transplantation with HLA antigen–mismatched donors [PDF]

, 2020
Brian Kornblit, Barry E. Storer, Niels Smedegaard Andersen, Michael B. Maris, Thomas R. Chauncey, Effie W. Petersdorf, Ann E. Woolfrey, Mary E.D. Flowers, Rainer Storb, David G. Maloney, Brenda M. Sandmaier   +10 more
openalex   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Nomenclature for Factors of the HLA System, 2026. [PDF]

HLA
Marsh SGE, Osoegawa K, Bodmer WF, Bontrop RE, Carrington MN, Erlich HA, Heidt S, Holdsworth R, Mayr WR, Maiers M, Parham P, Petersdorf EW, Robinson J, Trowsdale J, Fernández-Viña M.   +14 more
europepmc   +1 more source