Results 1 to 10 of about 102,746 (120)

Analysis of HLA-Ⅰ antibody specificity and estimation of antigen immunogenicity: 96 patients recieved genotype-matched platelet transfusions

open access: yesZhongguo shuxue zazhi, 2022
Objective To analyze the specificity of HLA class-Ⅰ antibody in the patients received HLA-matched platelet transfusions and estimate the relative immunogenicity of HLA-Ⅰ antigens.
Ying LIU   +6 more
doaj   +1 more source

Current research status of HLA in immune‐related diseases

open access: yesImmunity, Inflammation and Disease, 2021
Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
doaj   +1 more source

The HLA Ligandome Comprises a Limited Repertoire of O-GlcNAcylated Antigens Preferentially Associated With HLA-B*07:02

open access: yesFrontiers in Immunology, 2021
Mass-spectrometry based immunopeptidomics has provided unprecedented insights into antigen presentation, not only charting an enormous ligandome of self-antigens, but also cancer neoantigens and peptide antigens harbouring post-translational ...
Soumya Mukherjee   +9 more
doaj   +1 more source

Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]

open access: yesJournal of Nephropathology, 2012
Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi   +2 more
doaj   +1 more source

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens

open access: yesFrontiers in Immunology, 2020
Patients undergoing allogeneic stem cell transplantation as treatment for hematological diseases face the risk of Graft-versus-Host Disease as well as relapse. Graft-versus-Host Disease and the favorable Graft-versus-Leukemia effect are mediated by donor
Kyra J. Fuchs   +14 more
doaj   +1 more source

HLA class I and class II associations with ESRD in Saudi Arabian population. [PDF]

open access: yesPLoS ONE, 2014
Chronic renal failure (CRF) leads in the majority of instances to end stage renal disease (ESRD) requiring renal replacement therapy. Our interest was to evaluate the possible associations of HLA class I and class II antigens with ESRD independent of ...
Nuha Mahmoud Hamdi   +2 more
doaj   +1 more source

High maternal-fetal HLA eplet compatibility is associated with severe manifestation of preeclampsia

open access: yesFrontiers in Immunology, 2023
IntroductionPreeclampsia is responsible for more than 70 000 and 500 000 maternal and fetal deaths, respectively each year. Incomplete remodelling of the spiral arteries in placenta is the most accepted theory of preeclampsia pathogenesis.
Katarzyna Stefańska   +19 more
doaj   +1 more source

Effect of HLA-G5 Immune Checkpoint Molecule on the Expression of ILT-2, CD27, and CD38 in Splenic B cells

open access: yesJournal of Immunology Research, 2022
The human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with a complex network of interactions with several inhibitory receptors. Although the effect of HLA-G on T cells and NK cells is well studied, the effect of HLA-G on B cells is still
Hana Rohn   +8 more
doaj   +1 more source

PECULIARITIES OF HLA-PHENOTYPES IN PATIENTS WITH PYELONEPHRITIS [PDF]

open access: yesAnnals of Mechnikov's Institute, 2016
Introduction. Of great interest are the studies on the role of human leucocyte antigens (HLA) in pathogenesis of a disease. The kidneys is vulnerable to injury in the context of inflammatory responses, with the potential involvement of a number of ...
Haiseniuk F, Driyanska V, Kruglikov V
doaj   +1 more source

Measles virus epitope presentation by HLA: novel insights into epitope selection, dominance and microvariation

open access: yesFrontiers in Immunology, 2015
Immunity to infections with Measles Virus (MV) can involve vigorous HLA class I restricted CD8+ cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome.
Ingrid eSchellens   +17 more
doaj   +1 more source

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