Results 21 to 30 of about 12,564,476 (214)

Peculiarities of phenotypes of patients with pyelo- and glomerulonephritis by HLA distribution analysis

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2018
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis of chronic kidney disease (CKD) have demonstrated the associative links of the HLA antigens, which stipulate the relative and attributive risks of some autoimmune diseases ...
V. Driianska   +4 more
doaj   +1 more source

HLA-B*35-restricted CD8 T cell epitopes in the antigen 85 complex of Mycobacterium tuberculosis. [PDF]

open access: yes, 2001
Few target epitopes have been described for human CD8 T lymphocytes in antigens of Mycobacterium tuberculosis. By use of a reverse immunogenetics approach, 23 motif-bearing peptides of the Ag85 complex were tested for binding to HLA-B*35, one of the ...
Ogg, GS   +8 more
core   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN   +4 more
doaj   +1 more source

Public antigenic determinant on a family of HLA-B molecules. [PDF]

open access: yesJournal of Clinical Investigation, 1979
Serologic cross-reactivity among allelic gene products commonly occurs in the HLA complex, but the molecular basis of these serologic phenomena is incompletely characterized. Because of strong cross-reactivity among antigens comprising the B7 cross-reactive group (i.e., HLA-B7, Bw22, B27, B40, and Bw42) and because of the association of several ...
B D, Schwartz, L K, Luehrman, G E, Rodey
openaire   +2 more sources

FREQUENCY OF OCCURRENCE OF ANTIBODIES TO HLA ANTIGENS IN RECIPIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION

open access: yesМедицина в Кузбассе, 2023
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева   +7 more
doaj  

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

open access: yes, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A.   +56 more
core   +1 more source

DISTRIBUTION PATTERN FOR HLA SPECIFICITIES IN THE PATIENTS WITH ACUTE MYELOID LEUKEMIA

open access: yesМедицинская иммунология, 2019
The article presents a study on the distribution of gene polymorphisms in the histocompatibility antigens among the patients diagnosed with AML, and healthy donors in the Republic of Kazakhstan, as well as features of the HLA-A*, *B, Cw*, DRB1*, DQB1 ...
I. R. Ramilyeva   +5 more
doaj   +1 more source

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

open access: yes, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike   +11 more
core   +1 more source

Biosynthesis of HLA-A and HLA-B antigens in vivo.

open access: yesJournal of Biological Chemistry, 1980
The biosynthesis of the HLA-A and -B antigens was studied in the B lymphoblastoid cell line BRI 8 and the Burkitt lymphoma line DAudi. The heavy chains of the HLA-A and -B antigens were inserted asymmetrically into the rough endoplasmic reticulum of BRI 8 cells as transmembrane polypeptides.
M J, Owen   +2 more
openaire   +2 more sources

Differential role of HLA-A and HLA-B, C expression levels as prognostic markers in colon and rectal cancer

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Purpose The association of human leucocyte antigen (HLA) class I expression levels with the clinical course of many malignancies reflects their crucial role in the recognition and elimination of malignant cells by cognate T cells and NK cells.
Wilko Weichert   +10 more
doaj   +1 more source

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