Results 21 to 30 of about 144,091 (315)

Public antigenic determinant on a family of HLA-B molecules. [PDF]

Journal of Clinical Investigation, 1979
Serologic cross-reactivity among allelic gene products commonly occurs in the HLA complex, but the molecular basis of these serologic phenomena is incompletely characterized. Because of strong cross-reactivity among antigens comprising the B7 cross-reactive group (i.e., HLA-B7, Bw22, B27, B40, and Bw42) and because of the association of several ...
B D, Schwartz, L K, Luehrman, G E, Rodey
openaire   +2 more sources

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike, Bloemer, K, Messer, Gerald, Bloemer, Katharina, Messer, G, Ziegler, Andreas, Ragoussis, Jiannis, Ragoussis, J, Weiss, Elisabeth H., Pohla, H, Weiss, EH, Ziegler, A   +11 more
core   +1 more source

FREQUENCY OF OCCURRENCE OF ANTIBODIES TO HLA ANTIGENS IN RECIPIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION

Медицина в Кузбассе, 2023
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева, Алия Зинфировна Барканова, Григорий Валерьевич Вавин, Светлана Ивановна Елгина, Вадим Гельевич Мозес, Елена Владимировна Рудаева, Кира Борисовна Мозес, Наталья Степановна Черных   +7 more
doaj  

Biosynthesis of HLA-A and HLA-B antigens in vivo.

Journal of Biological Chemistry, 1980
The biosynthesis of the HLA-A and -B antigens was studied in the B lymphoblastoid cell line BRI 8 and the Burkitt lymphoma line DAudi. The heavy chains of the HLA-A and -B antigens were inserted asymmetrically into the rough endoplasmic reticulum of BRI 8 cells as transmembrane polypeptides.
M J, Owen, A M, Kissonerghis, H F, Lodish   +2 more
openaire   +2 more sources

DISTRIBUTION PATTERN FOR HLA SPECIFICITIES IN THE PATIENTS WITH ACUTE MYELOID LEUKEMIA

Медицинская иммунология, 2019
The article presents a study on the distribution of gene polymorphisms in the histocompatibility antigens among the patients diagnosed with AML, and healthy donors in the Republic of Kazakhstan, as well as features of the HLA-A*, *B, Cw*, DRB1*, DQB1 ...
I. R. Ramilyeva, Zh. K. Burkitbaev, S. A. Abdrakhmanova, A. A. Turganbekova, D. K. Baimukasheva, E. B. Zhiburt   +5 more
doaj   +1 more source

Differential role of HLA-A and HLA-B, C expression levels as prognostic markers in colon and rectal cancer

Journal for ImmunoTherapy of Cancer, 2022
Purpose The association of human leucocyte antigen (HLA) class I expression levels with the clinical course of many malignancies reflects their crucial role in the recognition and elimination of malignant cells by cognate T cells and NK cells.
Wilko Weichert, Lei Cai, Soldano Ferrone, Peter J K Kuppen, Lindy G Durrant, Theodoros Michelakos, Filippos Kontos, Tomohiro Kurokawa, Ananthan Sadagopan, Danielle Krijgsman, Cristina R Ferrone   +10 more
doaj   +1 more source

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef, Johnson, Judith P., Matthias Ulbrecht, Ulbrecht, Matthias, Josef Kellermann, Judith P. Johnson, Weiss, Elisabeth H., Elisabeth H. Weiss   +7 more
core   +1 more source

HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles [PDF]

Communications Biology, 2021
AbstractExtracellular vesicles can modulate diverse processes ranging from proliferation and tissue repair, to chemo-resistance and cellular differentiation. With the advent of tissue and immunological targeting, extracellular vesicles are also increasingly viewed as promising vectors to deliver peptide-based cancer antigens to the human immune system.
Julia Bauzá-Martinez, Albert J. R. Heck, Wei Wu   +2 more
openaire   +4 more sources

Evaluation of the humoral immune response to human leukocyte antigens in Brazilian renal transplant candidates. [PDF]

PLoS ONE, 2014
Pre-transplant sensitization to human leukocyte antigens (HLA) is a risk factor for graft failure. Studies of the immunological profile related to anti-HLA antibodies in Brazilian renal transplant candidates are few.
Patricia Keiko Saito, Roger Haruki Yamakawa, Erica Pereira Aparecida, Waldir Verissimo da Silva Júnior, Sueli Donizete Borelli   +4 more
doaj   +1 more source