Results 31 to 40 of about 144,091 (315)

Human Leukocyte Antigen (HLA) Frequencies and 4-loci HLA Haplotype Frequencies in Southern Thailand

open access: yesJournal of Health Science and Medical Research (JHSMR)
Objective: To determine the antigen and haplotype frequencies of human leukocyte antigen-A (HLA-A), -B, -DRB1, and -DQB1 in southern Thailand. Material and Methods: We retrospectively analyzed HLA typing data from patients treated at Songklanagarind ...
Kantarat Kusolthammarat   +4 more
doaj   +1 more source

Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients

open access: yesBrazilian Journal of Medical and Biological Research, 1998
A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty
E.A. Donadi   +4 more
doaj   +1 more source

Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity

open access: yeseLife, 2018
The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8+ T cells, inducing immunity against infections and cancers.
Brogan Yarzabek   +9 more
doaj   +1 more source

HLA-B Alleles Associated with the B15 Serologically Defined Antigens

open access: yesHuman Immunology, 1997
Cells expressing HLA molecules in the B15 family were identified by serologic typing in routine testing of volunteer donors of various ethnic backgrounds for a bone marrow registry. DNA sequencing was used to identify HLA-B15 alleles associated with each serologic type and to examine the diversity within the B15 antigen family.
N, Steiner   +5 more
openaire   +2 more sources

E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]

open access: yes, 2005
Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara   +9 more
core   +1 more source

Sonographic Pattern of Subacute Thyroiditis Is HLA-Dependent

open access: yesFrontiers in Endocrinology, 2019
Background: Since 1977 the susceptibility to SAT has been known to be HLA-B*35-related in ~70% of patients. Recently it has been demonstrated that SAT is associated with the presence of HLA-B*18:01 and DRB1*01, as well as with HLA-C*04:01.
Magdalena Stasiak   +6 more
doaj   +1 more source

Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran ...
Fatemeh Toghani Hulari   +4 more
doaj  

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B

open access: yesPLoS Pathogens, 2007
CD8(+) T cells are essential for host defense to intracellular bacterial pathogens such as Mycobacterium tuberculosis (Mtb), Salmonella species, and Listeria monocytogenes, yet the repertoire and dominance pattern of human CD8 antigens for these pathogens remains poorly characterized.
Deborah A Lewinsohn   +9 more
openaire   +4 more sources

Homozygosity in any HLA locus is a risk factor for specific antibody production: the taboo concept 2.0

open access: yesFrontiers in Immunology
ObjectiveIn a cooperative study of the University Hospital Leipzig, University of Leipzig, and the Charité Berlin on kidney transplant patients, we analysed the occurrence of HLA-specific antibodies with respect to the HLA setup of the patients. We aimed
Henry Loeffler-Wirth   +3 more
doaj   +1 more source

Analysis of HLA allele-specific antibodies and Eplets in patients with platelet transfusion refractoriness

open access: yesZhongguo shuxue zazhi, 2022
Objective To analyze the specificity and Eplets of HLA allele-specific antibody in patients with platelet transfusion refractoriness (PTR). Methods HLA-A and B genotypes were detected by PCR-SBT, and HLA-Ⅰ antibodies in patients′ serum were detected by ...
Bing ZHANG   +6 more
doaj   +1 more source

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