Results 231 to 240 of about 386,968 (310)

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Methodological strategies for mapping <i>HLA</i> susceptibility loci in vitiligo: A focused minireview. [PDF]

World J Methodol
Bouayad A.
europepmc   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Immunology of Normal Pregnancy and Preeclampsia and the Role of Placental Non-Classical HLA and Decidual NK Cells. [PDF]

Int J Mol Sci
Hackmon R, Geraghty DE, Dunk CE.
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Highly sensitized kidney transplant candidates: integrating acceptable mismatch, desensitization, imlifidase, and emerging immune-cell targeting strategies. [PDF]

Front Immunol
Reuter S, Lachmann N, de Ferrante H, Böhmig GA, Budde K.   +4 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Targeting non-canonical antigens unlocks functional T-cell responses in renal cell carcinoma. [PDF]

J Immunother Cancer
Wang J, Zhu Y, He X, Yin S, He Y, Yao P, Li J, Li X, Shi P, Qian R, Xiao Z, Ye X, Xi JJ, Ye B.   +13 more
europepmc   +1 more source

HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections. [PDF]

Nat Commun
Magyari B, Fülöp AT, Kókai D, Tóth F, Balogh GM, Andreu-Sánchez S, Innocenti G, Weersma RK, Fu J, Pál C, Zhernakova A, Vogl T, Manczinger M.   +12 more
europepmc   +1 more source

Extended Characterisation of the Coding Sequence of the HLA-C*04:238 Allele by Third-Generation Sequencing. [PDF]

HLA
Ferru-Clément R, Rivière L, Ratiarison D, Jollet I.   +3 more
europepmc   +1 more source