CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam+6 more
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On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni
The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital.
P. H. Cabello+3 more
doaj +1 more source
ALLOREACTIVE T LYMPHOCYTES CULTURED FROM LIVER TRANSPLANT BIOPSIES: ASSOCIATIONS OF HLA SPECIFICITY WITH CLINICOPATHOLOGICAL FINDINGS. [PDF]
Lymphocyte cultures grown from liver allograft biopsies were shown to exhibit alloreactivity towards donor cells as measured by primed lymphocyte testing (PLT). The PLT specificity was determined in assays using HLA typed panel cells and/or by inhibition
Demetris, A Jake+6 more
core
Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E.+4 more
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Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients
A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty
E.A. Donadi+4 more
doaj +1 more source
Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation [PDF]
Alloreactivity compromising clinical outcomes in stem cell transplantation is observed despite HLA matching of donors and recipients. This has its origin in the variation between the exomes of the two, which provides the basis for minor ...
AbdulRazzaq, Badar+17 more
core +1 more source
HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena+5 more
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Diversity in HLA class I and class II in kidney donors and recipients according to race in KwaZulu-Natal (South Africa) implications for transplantation [PDF]
HLA matching of donors and recipients plays a major role in the success of organ transplantation. Race differences inHLA have been reported elsewhere.Aim: To analyse the diversity of HLA Class I and Class II among kidney donors and recipients according ...
Allen, V+3 more
core +2 more sources
A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen [PDF]
NY-ESO-1 has been a major target of many immunotherapy trials because it is expressed by various cancers and is highly immunogenic. In this study, we have identified a novel HLA-B*1801-restricted CD8<sup>+</sup>T cell epitope, NY-ESO-1<sub&
Ashley J. Knights+18 more
core +9 more sources
Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler+18 more
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