Results 51 to 60 of about 1,300,736 (395)

Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival

open access: yesOncoImmunology, 2021
Immune checkpoint inhibitors (ICIs) have improved the survival of patients with non-small cell lung cancer (NSCLC) by reinvigorating tumor-specific T cell responses.
Fiamma Berner   +30 more
doaj   +1 more source

TripHLApan: predicting HLA molecules binding peptides based on triple coding matrix and transfer learning [PDF]

open access: yesarXiv, 2022
Human leukocyte antigen (HLA) is an important molecule family in the field of human immunity, which recognizes foreign threats and triggers immune responses by presenting peptides to T cells. In recent years, the synthesis of tumor vaccines to induce specific immune responses has become the forefront of cancer treatment.
arxiv  

Predicting Kidney Transplant Survival using Multiple Feature Representations for HLAs [PDF]

open access: yesProceedings of the 19th International Conference on Artificial Intelligence in Medicine (2021) 51-60, 2021
Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another transplant) for kidney transplantation is the compatibility of the Human Leukocyte Antigens (HLAs) between the ...
arxiv  

HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]

open access: yes, 2003
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena   +5 more
core   +2 more sources

HLA predictions from long sequence read alignments, streamed directly into HLAminer [PDF]

open access: yesarXiv, 2022
The rapidly changing landscape of sequencing technologies brings new opportunities to genomics research. Longer sequence reads and higher sequence throughput coupled with ever-improving base accuracy and decreasing per-base cost is now making long reads suitable for analyzing polymorphic regions of the human genome, such as those of the human leucocyte
arxiv  

Immunohistochemical identification of macrophages, lymphoid cells and HLA antigens in the human testis.

open access: yesInternational Journal of Andrology, 1987
The presence and distribution of macrophages, several subtypes of lymphocytes and HLA antigens in the human testis were studied using monoclonal antibodies and immunocytochemical staining.
P. Pöllänen, M. Niemi
semanticscholar   +1 more source

Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]

open access: yes, 2013
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E.   +4 more
core   +2 more sources

On the association between HLA-A1 and B5 and clinical forms of schistosomiasis mansoni

open access: yesMemorias do Instituto Oswaldo Cruz, 1991
The association between both HLA-A1 and B5 antigens and chronic forms of human schistosomiasis was studied in 64 patients and 26 normal controls from a southern Brazilian hospital.
P. H. Cabello   +3 more
doaj   +1 more source

Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]

open access: yes, 2018
Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il   +5 more
core   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

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