VASCULAR ENDOTHELIAL GROWTH FACTOR AND HLA-PHENOTYPE IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS
Український Журнал Нефрології та Діалізу, 2016 It was to determine associations the serum levels ofVEGF and with HLA inpatients with chronic glomerulonephritis and nephrotic syndrome (CGN, NS). Materials and methods.
М. Kolesnyk +6 more
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Dynamics-based peptide-MHC binding optimization by a convolutional variational autoencoder: a use-case model for CASTELO [PDF]
arXiv, 2020 An unsolved challenge in the development of antigen specific immunotherapies is determining the optimal antigens to target. Comprehension of antigen-MHC binding is paramount towards achieving this goal. Here, we present CASTELO, a combined machine learning-molecular dynamics (ML-MD) approach to design novel antigens of increased MHC binding affinity ...
arxiv
TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
BMC Bioinformatics, 2021 We previously developed TANTIGEN, a comprehensive online database cataloging more than 1000 T cell epitopes and HLA ligands from 292 tumor antigens. In TANTIGEN 2.0, we significantly expanded coverage in both immune response targets (T cell epitopes and ...
Guanglan Zhang +4 more
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Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]
, 2018 Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il +5 more
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Medicina v Kuzbasse, 2023 Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева +7 more
doaj
Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers. [PDF]
, 2020 The study objective was to test the hypothesis that having histocompatible children increases the risk of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), possibly by contributing to the persistence of fetal cells acquired during ...
Barcellos, Lisa F +16 more
core
Cultured Human Epidermal Cells Do Not Synthesize HLA-DR [PDF]
, 1982 All nucleated cells express HLA-A, B, and C antigens. However, only a few cells, including epidermal cells, demonstrate HLA-DR antigens which are potent transplantation immunogens in man.
Benike, Claudia J. +4 more
core +1 more source
HLA-A,-B,-C and -DR Antigens and Juvenile-Onset Diabetes Mellitus [PDF]
, 1981 The genetic region which exerts a major influence on graft rejection is known as the major histocompatibility complex or MHC. The MHC in man, the HLA system, includes at least five distinct multi-allelic loci, HLA-A,-B,-C,-D and -DR.
Solow, Lucius Henry
core
HLA typing in systemic sclerosis
Reumatismo, 2001 Objective: the aim of the study was to investigate the relationship between Systemic Sclerosis (SSc) and HLA antigens, and to correlate these antigens with the clinical manifestations of the disease.
E. Favalli +4 more
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Distribution of HLA epitope frequencies in Turkish population
Türk Biyokimya Dergisi, 2022 The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens.
Oguz Fatma Savran +7 more
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