Expression of HMB45, MelanA and SOX10 is rare in non-small cell lung cancer [PDF]
Background Non-small cell lung cancer (NSCLC) and melanoma are frequent entities in routine diagnostics. Whereas the differential diagnosis is usually straight forward based on histomorphology, it can be challenging in poorly differentiated tumors as ...
Mark Kriegsmann +10 more
doaj +3 more sources
Efficacy of hormonal suppression in a patient with chyluria due to lymphangioleiomyomatosis [PDF]
Lymphangioleiomyomatosis (LAM) is a rare lung disease affecting almost exclusively young women, characterised by abnormal proliferation of atypical smooth muscle cells.
Contini Paola +7 more
doaj +2 more sources
UTERINE PERIVASCULAR EPITHELIOID CELL TUMOR:A CASE REPORT [PDF]
Perivascular epithelioid cell tumor (PEComa) is composed of HMB45+ epithelioid cells with clear to granular cytoplasm and perivascular distribution.
G. Iravanlo Z. Nozarian
doaj +3 more sources
A rare case of a laryngeal angiomyolipoma
Laryngeal angiomyolipoma is a rare tumor with few reported cases in the literature. The case report explains a 62‐year‐old man who presents with dyspnea and found to have a laryngeal angiomyolipoma staining CD34 positive, but HMB45 and Melan‐A negative.
Lillian McCampbell +2 more
doaj +2 more sources
Conventional renal cell carcinoma with renal capsular leiomyoma: A diagnostic dilemma
Primary renal leiomyomas are very rare benign tumors of the kidney, arising from smooth muscle cells of the renal capsule, pelvis or blood vessels. Simultaneous occurrence of a leiomyoma with conventional renal cell carcinoma (RCC) in the same kidney is ...
Vijay K Maneesh +3 more
doaj +2 more sources
To select the optimal immunohistochemical staining method for pigmented melanoma
Melanin granules may be difficult to distinguish from the brown reaction product of 3,3’-diaminobenzidine (DAB) in immunostaining. To identify a reliable immunostaining protocol for pigmented melanoma that preserves tissue integrity while enabling clear ...
Juan Lin, Zhijie You, Xin Chen
doaj +2 more sources
siRNA-mediated downregulation of HMB45 in differentiated ADSCs.
siRNA resulted in the downregulation of HMB45 in undifferentiated ADSCs and differentiated ADSCs.
Yuri Ikeda (7360736) +5 more
core +1 more source
Comparative analysis of BCL2, Cyclin D1, P53 and HMB45 expression in pigmented nevi and malignant melanoma of the skin, importance for diagnostic practice [PDF]
Pigmented tumors are a large group characterized by extensive morphological diversity, which makes their diagnosis difficult. There are malignant pigmented tumors morphologically mimicking benign lesions, as well as pigmented neoplasms with benign ...
Petkova, Lilyana; Medical University of Varna
core +4 more sources
Hepatic perivascular epithelioid cell tumor (PEComa): a case report with a review of literatures [PDF]
Hepatic perivascular epithelioid cell tumors (PEComas) are very rare. We report a primary hepatic PEComa with a review of the literature. A 56-year-old women presented with a nodular mass detected during the management of chronic renal failure and ...
Hyun-Jin Son +4 more
doaj +1 more source
HMB45/PRAME, a Novel Double Staining for the Diagnosis of Melanocytic Neoplasms: Technical Aspects, Results, and Comparison With Other Commercially Available Staining (PRAME and Melan A/PRAME) [PDF]
: PRAME (PReferentially expressed Antigen in MElanoma) is a tumor-associated antigen that was recently found to be expressed by malignant melanocytic lesions but not by benign ones, thus resulting useful in this diagnostic field.
Costantino Ricci +11 more
core +1 more source

