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Nature Reviews Cancer, 2015 In humans, the S100 protein family is composed of 21 members that exhibit a high degree of structural similarity, but are not functionally interchangeable. This family of proteins modulates cellular responses by functioning both as intracellular Ca(2+) sensors and as extracellular factors.
, Anne Bresnick, Bresnick Anne R
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S100 Proteins in the Epidermis [PDF]
Journal of Investigative Dermatology, 2004 The S100 proteins comprise a family of 21 low molecular weight (9-13 kDa) proteins that are characterized by the presence of two calcium-binding EF-hand motifs. Fourteen S100 protein genes are located within the epidermal differentiation complex on human chromosome 1q21 and 13 S100 proteins (S100A2, S100A3, S100A4, S100A6, S100A7, S100A8, S100A9 ...
Ann-Marie Broome +2 more
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S100 Proteins in Alzheimer’s Disease [PDF]
Frontiers in Neuroscience, 2019 S100 proteins are calcium-binding proteins that regulate several processes associated with Alzheimer’s disease (AD) but whose contribution and direct involvement in disease pathophysiology remains to be fully established.
Joana S. Cristóvão +3 more
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S100 Proteins As an Important Regulator of Macrophage Inflammation
Frontiers in Immunology, 2018 The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of intracellular and extracellular functions through regulating calcium balance, cell apoptosis, migration, proliferation, differentiation, energy metabolism, and ...
Jixin Zhong +2 more
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S100 Proteins in Acute Myeloid Leukemia
Neoplasia: An International Journal for Oncology Research, 2018 The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription factors, inflammation, chemotaxis,
Annette K. Brenner, Øystein Bruserud
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An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule [PDF]
Journal of Clinical and Diagnostic Research, 2022 Granular Cell Tumour (GCT) of nasal and paranasal area is an extremely rare entity, while the most common site is the tongue in oral cavity. GCT was first time described by Abrikossoff in 1926, which occurs in 3rd to 5th decades of life and most ...
Pooja Agarwal +3 more
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Developmental and Innervation Changes in the Circumvallate Papilla of Turmeric Treated diabetic Rats' Offspring versus Untreated :A Randomized Animal Controlled Trial [PDF]
The Egyptian Journal of Histology, 2021 Background: Diabetes mellitus has a deleterious effect on the offspring including a high tendency for abnormalities and a defected immune system. The current study was performed to investigate the effect of maternal diabetes on the development and the ...
Nad Marzouk, Zoba Ali, Marwa Abbass
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Indeterminate dendritic cell tumor (IDCT) [PDF]
Vestnik Dermatologii i Venerologii, 2023 Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women.
Evgenia V. Okladnikova +4 more
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Land, 2021 Spatial planning conducted by the local authorities has been identified as a key part of shaping carbon-neutral societies. Nevertheless, the question of whether local authorities are building their institutional capacity for integrating climate change ...
Vincent Wretling, Berit Balfors
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Potential Role of the Epidermal Differentiation Complex in the Pathogenesis of Psoriasis
Frontiers in Bioscience-Landmark, 2022 The skin is the largest barrier organ of the human body and serves to protect the internal structure of the body from the harmful environment. The epidermis forms the outermost layer and is exposed to the environment.
Deqiao Qin, Ling Ma, Li Qin
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