Results 41 to 50 of about 63,229 (163)

A case of large diffuse cutaneous neurofibroma masquerading as plexiform variant: Diagnostic challenges [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University
Diffuse Cutaneous Neurofibroma (DCN) is an infrequently encountered clinical entity that can be challenging to diagnose due to its variable clinical presentation, radiological findings, and histopathological features.
Shivani S Rao , Ranjana S Ranade
doaj  

A Study to Delineate the Immunohistological Parameters of Active Versus Stable Vitiligo Using S100, Melan A in Conjunction with CD4 and CD8 Immunohistochemistry Markers

open access: yesIndian Dermatology Online Journal
Background: Vitiligo is an autoimmune pigmentary disorder where it is important to assess the disease status (active/stable) to guide therapeutic decisions.
Sai Jyoti   +4 more
doaj   +1 more source

Extracellular S100β Disrupts Bergman Glia Morphology and Synaptic Transmission in Cerebellar Purkinje Cells

open access: yesBrain Sciences, 2019
Astrogliosis is a pathological process that affects the density, morphology, and function of astrocytes. It is a common feature of brain trauma, autoimmune diseases, and neurodegeneration including spinocerebellar ataxia type 1 (SCA1), a poorly ...
Olga S. Belozor   +7 more
doaj   +1 more source

S100 proteins in health and disease [PDF]

open access: yesAmino Acids, 2010
One class of proteins that has been increasingly emerging as a potentially important group of both molecular key players and biomarkers in the etiology, progression, manifestation and therapy of various inflammatory, neurodegenerative, metabolic and neoplastic disorders is the S100 family.
openaire   +2 more sources

Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family. [PDF]

open access: yesPLoS ONE, 2016
The S100 proteins are a large family of signaling proteins that play critical roles in biology and disease. Many S100 proteins bind Zn2+, Cu2+, and/or Mn2+ as part of their biological functions; however, the evolutionary origins of binding remain obscure.
Lucas C Wheeler   +3 more
doaj   +1 more source

Giant Lipoleiomyoma of Cervix Mimicking as Schwannoma: First Case Report of a Dual Morphologic Variant

open access: yesJournal of Mid-Life Health
Leiomyomas with schwannoma-like features are very rare and can resemble peripheral nerve sheath tumors, particularly if the characteristics of Verocay bodies and nuclear palisading are present.
Manupriya Sharma   +3 more
doaj   +1 more source

The Pharmacokinetic Profile of Freeze-dried Cyclosporine A-Eudragit S100 Nanoparticle Formulation in Dogs

open access: yesNano Biomedicine and Engineering, 2011
The pharmacokinetic profile of freeze-dried cyclosporine A-Eudragit S100 nanoparticles (CyA-S100-NP)was studied with a random two-way crossover study in dogs.
Yang Liu   +5 more
doaj   +1 more source

An integrated biomarker-based prognostic scale for assessing the risk of severe COVID-19 in children

open access: yesZdorovʹe Rebenka
Background. Despite available data, the problem of early prediction of COVID-19 severity in the pediatric population remains unresolved. The purpose was to assess the prognostic significance of NSE, S100, IFABP, NGAL, and E-selectin biomar­kers in ...
V.V. Yevtushenko   +4 more
doaj   +1 more source

Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells

open access: yesScientific Reports, 2017
Articular chondrocytes are slowly dividing cells that tend to lose their cell type-specific phenotype and ability to produce structurally and functionally correct cartilage tissue when cultured.
Juha Piltti   +4 more
doaj   +1 more source

Structural and functional diversification in the teleost S100 family of calcium-binding proteins

open access: yesBMC Evolutionary Biology, 2008
Background Among the EF-Hand calcium-binding proteins the subgroup of S100 proteins constitute a large family with numerous and diverse functions in calcium-mediated signaling.
Korsching Sigrun I   +2 more
doaj   +1 more source

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