Results 61 to 70 of about 65,795 (216)

KIF1A‐Mediated Axonal Transport of Netrin‐1 in iPSC‐Derived Human Forebrain Neurons

Cytoskeleton, EarlyView.
ABSTRACT Netrin‐1 is a secreted laminin‐like protein that functions as a guidance cue for axon pathfinding in development. Netrin‐1 also modulates synapse formation in developing neurons and long‐term potentiation in mature neurons. Netrin‐1 is expressed in human neurons; however, its intracellular distribution and trafficking have not been assessed ...
T. Y. Leung, J. Sidhu, A. Hsieh, Y. Ma, J. Liu, M. A. Silverman   +5 more
wiley   +1 more source

Giant Lipoleiomyoma of Cervix Mimicking as Schwannoma: First Case Report of a Dual Morphologic Variant

Journal of Mid-Life Health
Leiomyomas with schwannoma-like features are very rare and can resemble peripheral nerve sheath tumors, particularly if the characteristics of Verocay bodies and nuclear palisading are present.
Manupriya Sharma, Anita Chaudhary, Chanderdeep Sharma, Harpreet Kaur   +3 more
doaj   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath, Azfar Neyaz, Samer Khader   +2 more
wiley   +1 more source

Langerhans Cell Histiocytosis Masquerading as a Spinal Tumour in a Young Adult : A Case Report

GAIMS Journal of Medical Sciences
Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder of dendritic cells, predominantly affecting children. Adult spinal involvement is uncommon and may radiologically mimic malignant lesions.
Bhushan M. Warpe, Shweta S. Joshi
doaj   +1 more source

Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells

Scientific Reports, 2017
Articular chondrocytes are slowly dividing cells that tend to lose their cell type-specific phenotype and ability to produce structurally and functionally correct cartilage tissue when cultured.
Juha Piltti, Joakim Bygdell, Cecilia Fernández-Echevarría, Daniel Marcellino, Mikko J. Lammi   +4 more
doaj   +1 more source

S100 Proteins in Alzheimer’s Disease

Frontiers in Neuroscience, 2019
S100 proteins are calcium-binding proteins that regulate several processes associated with Alzheimer’s disease (AD) but whose contribution and direct involvement in disease pathophysiology remains to be fully established.
Joana S. Cristóvão, Joana S. Cristóvão, Cláudio M. Gomes, Cláudio M. Gomes   +3 more
doaj   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble, Samantha L. Payne, Matthew K. Vickaryous   +2 more
wiley   +1 more source

Hydride Materials for Advanced Electrochemical Energy Storage: Progress and Perspectives

EcoEnergy, EarlyView.
Hydrides are emerging as functional materials for low‐carbon electrochemical energy storage. Complex hydrides provide polyanionic electrolyte frameworks for all‐solid‐state, Li–S, and multivalent batteries; hydride ion conductors enable H− transport for emerging hydride‐based cells; and metal hydrides offer established electrode chemistries for Ni–MH ...
Taehyun Kim, Taegyoung Lee, Huijeong Oh, Shin‐ichi Orimo, Sangryun Kim   +4 more
wiley   +1 more source

Serum methylmalonic acid levels and epilepsy prevalence: Association analysis, exploratory mediation, and clinical corroboration

Epileptic Disorders, EarlyView.
Abstract Objective This study aimed to investigate the association between methylmalonic acid (MMA) and epilepsy prevalence and to explore potential inflammatory and nutritional pathways underlying this association. Methods This study included adults aged ≥ 20 years from the National Health and Nutrition Examination Survey (NHANES) 2011–2014.
Ningyu Wei, Ning Huang, Haipeng Chen, Rui Tang, Yuan Cheng, Xiang Zhang   +5 more
wiley   +1 more source