Results 81 to 90 of about 76,529 (293)

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

An integrated biomarker-based prognostic scale for assessing the risk of severe COVID-19 in children

Zdorovʹe Rebenka
Background. Despite available data, the problem of early prediction of COVID-19 severity in the pediatric population remains unresolved. The purpose was to assess the prognostic significance of NSE, S100, IFABP, NGAL, and E-selectin biomar­kers in ...
V.V. Yevtushenko, S.O. Kramarov, I.Yu. Seriakova, L.O. Palatna, M.O. Dudnikova   +4 more
doaj   +1 more source

S100 proteins in health and disease [PDF]

Amino Acids, 2010
One class of proteins that has been increasingly emerging as a potentially important group of both molecular key players and biomarkers in the etiology, progression, manifestation and therapy of various inflammatory, neurodegenerative, metabolic and neoplastic disorders is the S100 family.
openaire   +2 more sources

Extracellular S100β Disrupts Bergman Glia Morphology and Synaptic Transmission in Cerebellar Purkinje Cells

Brain Sciences, 2019
Astrogliosis is a pathological process that affects the density, morphology, and function of astrocytes. It is a common feature of brain trauma, autoimmune diseases, and neurodegeneration including spinocerebellar ataxia type 1 (SCA1), a poorly ...
Olga S. Belozor, Dariya A. Yakovleva, Ilya V. Potapenko, Andrey N. Shuvaev, Marina V. Smolnikova, Alex Vasilev, Elena A. Pozhilenkova, Anton N. Shuvaev   +7 more
doaj   +1 more source

Prognostic Value of S100 Family mRNA Expression in Hepatocellular Carcinoma

Background/Aims: The S100 family contains more than 20 Ca2+-binding proteins that participate in numerous cellular biological processes. However, the prognostic value of individual S100s in hepatocellular carcinoma (HCC) remains unclear.
Lingyan Ren, Hai Qian, Renrui Wan, Jian Zhang, Xiaofeng Zhu, Peng Li, Ping Xie, Zhenhua Tan   +7 more
core   +1 more source

Mapping the distribution of Meissner corpuscles throughout the human hand: Sex‐ and age‐dependent variations

The Anatomical Record, EarlyView.
Abstract Meissner corpuscles are rapidly adapting mechanoreceptors involved in tactile discrimination in human glabrous hand skin. Detailed information on their regional distribution and variation across age, sex, and hand side remains limited. This study mapped Meissner corpuscles in 17 phalangeal and palmar regions from 46 individuals (27 male and 19
Irene Amigo, Yolanda García‐Mesa, Patricia Cuendias, Jorge Feito, Olivia García‐Suárez, Iván Suazo, Zulima Fernández, José A. Vega   +7 more
wiley   +1 more source

Unmasking adenoid cystic carcinoma on lip mimicking as reactive lesion – A case report and review of literature

SRM Journal of Research in Dental Sciences
Rationale: Among salivary gland malignancies, adenoid cystic carcinoma (ADCC) is a particularly uncommon entity in the lip region, representing approximately 1% of malignant neoplasms in the head and neck.
Akalya Purushothaman, Sahana N. Srinath, Jyoti Tahasildar, Ninad Vijay Chavan, Savita S. Shiragur   +4 more
doaj   +1 more source

A Ki-67 és az S100 koexpressziós vizsgálata bőrelváltozásokban

, 2017
A bőrpatológiában a hasonló morfológia és lokalizáció miatt gyakran nehézséget okoz a melanoma in situ és a dysplasticus naevus elkülönítése. Ismert, hogy a melanoma proliferációs aktivitása magasabb, mint a naevusé, ezért munkám során megvizsgáltam a Ki-
Sós, László
core  

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells.

, 2004
The extracellular functions of S100 proteins have attracted more attention in recent years. S100 proteins are a group of calcium-binding proteins which exhibit cell- and tissue-specific expression, and different expression levels of members from this ...
Schäfer BW, Weigle B, Heizmann CW, Hsieh HL   +3 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source