Results 1 to 10 of about 37,117 (136)
S100 proteins in cardiovascular diseases [PDF]
Molecular Medicine, 2023 Cardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focus for public health experts.
Yue Zhou +5 more
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Pathogenic role of S100 proteins in psoriasis [PDF]
Frontiers in Immunology, 2023 Psoriasis is a chronic inflammatory skin disease. The histopathological features of psoriasis include excessive proliferation of keratinocytes and infiltration of immune cells.
Huifang Liang +5 more
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S100 Proteins in the Pathogenesis of Psoriasis and Atopic Dermatitis [PDF]
Diagnostics, 2023 The skin, the outermost layer of the human body, is exposed to various external stimuli that cause inflammatory skin reactions. These external stimulants trigger external epithelial cell damage and the release of intracellular substances.
Natsuko Saito-Sasaki, Yu Sawada
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S100 Proteins in Alzheimer’s Disease [PDF]
Frontiers in Neuroscience, 2019 S100 proteins are calcium-binding proteins that regulate several processes associated with Alzheimer’s disease (AD) but whose contribution and direct involvement in disease pathophysiology remains to be fully established.
Joana S. Cristóvão +3 more
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Relationship of S100 Proteins with Neuroinflammation [PDF]
BiomoleculesS100 proteins, a family of Ca2+-binding proteins, play numerous roles in cellular processes such as proliferation, differentiation, and apoptosis. Recent evidence has highlighted their critical involvement in neuroinflammation, a pathological hallmark of
Mario García-Domínguez
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S100 Proteins As an Important Regulator of Macrophage Inflammation [PDF]
Frontiers in Immunology, 2018 The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of intracellular and extracellular functions through regulating calcium balance, cell apoptosis, migration, proliferation, differentiation, energy metabolism, and ...
Chang Xia +5 more
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S100 Proteins in Acute Myeloid Leukemia [PDF]
Neoplasia: An International Journal for Oncology Research, 2018 The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription factors, inflammation, chemotaxis,
Annette K. Brenner, Øystein Bruserud
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Nature Reviews Cancer, 2015 In humans, the S100 protein family is composed of 21 members that exhibit a high degree of structural similarity, but are not functionally interchangeable. This family of proteins modulates cellular responses by functioning both as intracellular Ca(2+) sensors and as extracellular factors.
, Anne Bresnick, Bresnick Anne R
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Functions of S100 Proteins [PDF]
Current Molecular Medicine, 2013 The S100 protein family consists of 24 members functionally distributed into three main subgroups: those that only exert intracellular regulatory effects, those with intracellular and extracellular functions and those which mainly exert extracellular regulatory effects.
Guglielmo Sorci, Rosario Donato
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Erythropoietin Interacts with Specific S100 Proteins [PDF]
Biomolecules, 2022 Erythropoietin (EPO) is a clinically significant four-helical cytokine, exhibiting erythropoietic, cytoprotective, immunomodulatory, and cancer-promoting activities.
Alexey S. Kazakov +8 more
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