Results 31 to 40 of about 37,201 (219)

Intrinsically disordered and aggregation prone regions underlie β-aggregation in S100 proteins. [PDF]

PLoS ONE, 2013
S100 proteins are small dimeric calcium-binding proteins which control cell cycle, growth and differentiation via interactions with different target proteins.
Sofia B Carvalho, Hugo M Botelho, Sónia S Leal, Isabel Cardoso, Günter Fritz, Cláudio M Gomes   +5 more
doaj   +1 more source

The role of S100 proteins and their receptor RAGE in pancreatic cancer [PDF]

Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2015
Stefan Vetter
exaly   +2 more sources

Study of serum levels and skin expression of S100B protein in psoriasis [PDF]

Anais Brasileiros de Dermatologia, 2017
Background: S100B protein was reported to be elevated in psoriatic patients' serum, with no previous evaluation of its skin expression, in contrast to the extensively studied S100 protein.
Samar Abdallah M. Salem, Ekramy Ahmed El-Khateeb, Mervat Harvy, Hanaa Mohamed El-Sayed Emam, Wafaa Abdelaal, Reham El Nemr, Omneya Osama El-Hagry   +6 more
doaj   +1 more source

Interaction of S100A6 Protein with the Four-Helical Cytokines

Biomolecules, 2023
S100 is a family of over 20 structurally homologous, but functionally diverse regulatory (calcium/zinc)-binding proteins of vertebrates. The involvement of S100 proteins in numerous vital (patho)physiological processes is mediated by their interaction ...
Alexey S. Kazakov, Evgenia I. Deryusheva, Victoria A. Rastrygina, Andrey S. Sokolov, Maria E. Permyakova, Ekaterina A. Litus, Vladimir N. Uversky, Eugene A. Permyakov, Sergei E. Permyakov   +8 more
doaj   +1 more source

Large-scale proteomic identification of S100 proteins in breast cancer tissues

BMC Cancer, 2010
Background Attempts to reduce morbidity and mortality in breast cancer is based on efforts to identify novel biomarkers to support prognosis and therapeutic choices.
Cancemi Patrizia, Di Cara Gianluca, Albanese Nadia, Costantini Francesca, Marabeti Maria, Musso Rosa, Lupo Carmelo, Roz Elena, Pucci-Minafra Ida   +8 more
doaj   +1 more source

S100 Calcium-Binding Proteins and Ion Channels

Frontiers in Pharmacology, 2012
S100 Ca2+-binding proteins have been associated with a multitude of intracellular Ca2+-mediated functions including regulation of the cell cycle, cell differentiation, cell motility and apoptosis, modulation of membrane-cytoskeletal interactions ...
Anton eHermann, Rosario eDonato, Thomas M. Weiger, Walter J. Chazin   +3 more
doaj   +1 more source

Role of S100 family proteins in colorectal cancer (CRC): an overview of their potential function as new biomarkers and therapeutic agents

Expert Reviews in Molecular Medicine
Colorectal cancer (CRC) is the second deadliest cancer worldwide, posing a great threat to human health and a social burden. Various genetic and epigenetic alterations can activate tumourigenesis-related signalling pathways, leading to CRC development ...
Hamideh Raeisi, Leili Rejali, Nayeralsadat Fatemi, Amir Sadeghi, Zahra Sadeghloo, Mohammad Reza Zali, Ehsan Nazemalhosseini Mojarad   +6 more
doaj   +1 more source

Role of the S100 protein family in rheumatoid arthritis

Arthritis Research & Therapy, 2022
Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by synovial hyperplasia, inflammatory cell infiltration, and proliferation of inflammatory tissue (angiogranuloma).
Yuan-yuan Wu, Xiao-feng Li, Sha Wu, Xue-ni Niu, Su-qin Yin, Cheng Huang, Jun Li   +6 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source