Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer
We report on some of the optical properties of Hemoporfin (hematoporphyrin monomethyl ether, HMME), a photodynamic therapy (PDT) photosensitizer that has been in clinical trials in China since the early 1990s. We characterized the photosensitizer on the basis of one- and two-photon absorption and fluorescence emission.
Tim C Lei
exaly +3 more sources
Comparing the clinical efficacy of hemoporfin-mediated photodynamic therapy for port wine stains in children with prior pulsed dye laser treatment history [PDF]
BackgroundHemoporfin-mediated photodynamic therapy (HMME-PDT) is an effective and safe therapeutic modality for port wine stains (PWS). However, the clinical efficacy is influenced by multiple factors.
Xiuwei Wang +6 more
doaj +2 more sources
Comparison of the effects of hemoporfin-mediated photodynamic and Vbeam pulsed dye laser in the treatment of port-wine stains: a retrospective analysis [PDF]
Background The pulsed dye laser (PDL) is widely regarded as the gold standard treatment for port wine stain (PWS); however, its therapeutic efficacy exhibits considerable variability.
Yantao Ding +4 more
doaj +2 more sources
Comparing HMME-PDT and Cynergy dual-wavelength laser in the treatment of facial PWS
Pulsed dye laser (PDL) is the gold-standard therapy for port-wine stains (PWSs), but the therapeutic efficacies vary widely with each individual. Recent studies suggest that hematoporphyrin monomethyl ether-photodynamic therapy (HMME-PDT) is an effective alternative in the treatment of PWS.
Xiaoming Liu
exaly +3 more sources
Comparative analysis of metabolome and transcriptomes to explore the inhibited influence of sonodynamic therapy combined with lonidamine on hepatocellular carcinoma [PDF]
Sonodynamic therapy (SDT) has emerged as a promising approach for treating hepatocellular carcinoma (HCC) by combining sonosensitizers with low-intensity ultrasound. However, SDT alone could not achieve satisfactory results.
Haoyan Tan +5 more
doaj +2 more sources
Influential Factors in the Efficacy and Safety of Hemoporfin-Mediated Photodynamic Therapy for Facial Port-Wine Stains. [PDF]
ABSTRACT Background Hemoporfin‐mediated photodynamic therapy (HMME‐PDT) is a novel and promising treatment for port‐wine stains (PWS); however, the factors affecting the efficacy and safety are controversial. Aim In this study, the relationship between influential factors and the efficacy and safety of HMME‐PDT for facial PWS was clarified.
You R +10 more
europepmc +2 more sources
Sono-Controllable Janus Hydrogel Platform for Sequential Tumor Eradication and Bone Regeneration in Metastatic Breast Cancer. [PDF]
Sequential tumor eradication and bone regeneration remain a significant challenge for patients with breast cancer bone metastases. This study develops a novel Janus hydrogel platform, which can achieve tumor elimination and bone repair under the action of different ultrasound frequencies.
Li Y +12 more
europepmc +2 more sources
A clinical study of HMME-PDT therapy in Chinese pediatric patients with port-wine stain
To report our observations from a trial of the effectiveness and safety of hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) in treating Chinese Pediatric patients port-wine stains (PWS).From October 2017 to December 2017, the study recruited 82 patients of PWS with negative HMME skin test results.
Gan, Li-Qiang +3 more
exaly +3 more sources
Efficacy and safety of hemoporfin photodynamic therapy in treating port-wine stains in Chinese children: a systematic review and meta-analysis [PDF]
ObjectiveThe purpose of this study is to explore the efficacy and safety of hematoporphyrin monomethyl ether mediated photodynamic therapy (HMME-PDT) in treating children with port-wine stains (PWS).MethodLiterature related to the topic was searched in ...
Jing Xu, Hongxin Li
doaj +2 more sources
The aim of this study was to compare the sensitivity of hematoporphyrin monomethyl ether (HMME)-mediated PDT in the Epstein-Barr virus (EBV) positive and negative human nasopharyngeal carcinoma (NPC) cells.The intracellular uptake of HMME in C666-1 (EBV+) and CNE2 (EBV-) cells was quantitatively determined after incubating with different concentration ...
Buhong Li, Zheng Huang
exaly +3 more sources

