Enhanced Cerenkov radiation induced photodynamic therapy based on GSH-responsive biomimetic nanoplatform to trigger immunogenic cell death for tumor immunotherapy [PDF]
Cerenkov radiation (CR) can serve as a source of internal light to overcome the limited tissue penetration of external light in conventional photodynamic therapy (PDT).
Ruijie Qian +8 more
doaj +2 more sources
Ultrasound-Triggered Nanocomposite "Lever" Hydrogels with a Full Repair System Accelerates Diabetic Foot Ulcer Repair. [PDF]
Ultrasound (US)‐treated nanocomposite ‘lever’ hydrogels reprogrammed wound reactive oxygen species (ROS) levels and promoted wound healing in infected diabetic foot ulcers. Abstract Diabetic foot ulcers (DFUs) are a complex mixture of neuropathy, peripheral arterial disease, and infection, where excessive reactive oxygen species (ROS) exacerbates ...
Shen Y +16 more
europepmc +2 more sources
Design of Wood-Based Gd (III)-Hemoporphyrin Monomethyl Ether Eco-Material for Optical Oxygen Sensing with a Wide Detection Range [PDF]
Gaseous oxygen detection is essential in numerous production and manufacturing sectors. To meet the varying oxygen detection requirements across different fields, techniques that offer a wide oxygen detection range should be developed.
Yujie Niu +3 more
doaj +2 more sources
Sonodynamic effect of hematoporphyrin monomethyl ether on ligature-induced periodontitis in rats [PDF]
Deshu Zhuang,1 Jialong Han,1 Liangjia Bi,1 Yueping Wang,1 Yanru Hao,2 Qi Zhou,3 Wenwu Cao3,4 1Department of Stomatology, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, People’s Republic of China; 2Department of Stomatology, The
Zhuang DS +6 more
doaj +3 more sources
Image-guided therapy of colorectal cancer using a zirconium coordinated nanosensitizer [PDF]
Sonodynamic therapy (SDT) has gained attention as a promising non-invasive cancer treatment strategy due to its localized effects and superior tissue penetration.
Shuyang Yang +7 more
doaj +2 more sources
Efficacy and related factors analysis in HMME-PDT in the treatment of port wine stains
To observe the efficiency and safety of hematoporphyrin mono-methylether photodynamic therapy (HMME-PDT) in treating port-wine stains (PWS) with Chinese patients, and to evaluate the advantage of photograph,VISIA Complexion Analysis System, and dermoscopy in efficacy evaluation.Analyzing changes of pain during treatment and related adverse reactions.62
Nong Xiang
exaly +3 more sources
Clinical study on clinical operation and post-treatment reactions of HMME-PDT in treatment of PWS
To analyze the clinical efficacy of hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) in treating port-wine stains (PWS), and its clinical operation skills and operation essentials.A total of 16 cases of PWS with negative HMME skin test results were included in this study.
Yunjie, Zhang +5 more
exaly +3 more sources
The penetration effect of HMME-mediated low-frequency and low-intensity ultrasound against the Staphylococcus aureus bacterial biofilm [PDF]
Background The purpose of this study was to observe the effect of hematoporphyrin monomethyl ether (HMME)-mediated low-frequency and low-intensity ultrasound on mature and stable Staphylococcus aureus (S.
Tao Wang +3 more
doaj +3 more sources
An alternative way to break the matrix barrier: an experimental study of a LIFU-mediated, visualizable targeted nanoparticle synergistic amplification for the treatment of malignant fibroblasts [PDF]
Malignant fibroblasts (MFs) are widely present in various diseases and are characterized by connective tissue proliferation; these cells act as a physical barrier that severely limits drug delivery and affects disease outcomes.
Xiangzhi Zhao +6 more
doaj +2 more sources
pH-driven butterfly effect for cascade-amplified tumor therapy based on thalidomide coordinated Fe-HMME nanoplatform. [PDF]
A promising approach for treating intractable cancers has been presented by photodynamic therapy (PDT). However, the limited penetration depth of PDT and suboptimal monotherapy efficacy of PDT significantly restrict its clinical applications. In this study, we constructed an acidic tumor microenvironment (TME)-activated carrier-free nanoplatform (HMME ...
Qu B +7 more
europepmc +3 more sources

