Results 91 to 100 of about 11,358 (217)

Human metapneumovirus infection of organoid-derived human bronchial epithelium represents cell tropism and cytopathology as observed in in vivo models

mSphere
Human metapneumovirus (HMPV), a member of the Pneumoviridae family, causes upper and lower respiratory tract infections in humans. In vitro studies with HMPV have mostly been performed in monolayers of undifferentiated epithelial cells.
Pau Ribó-Molina, Stefan van Nieuwkoop, Anna Z. Mykytyn, Peter van Run, Mart M. Lamers, Bart L. Haagmans, Ron A. M. Fouchier, Bernadette G. van den Hoogen   +7 more
doaj   +1 more source

Human Metapneumovirus Attachment Protein Contributes to Neutrophil Recruitment into the Airways of Infected Mice

Viruses, 2017
Human Metapneumovirus (HMPV) is a leading respiratory pathogen that causes lower respiratory tract infections worldwide. Acute HMPV infection induces an exacerbated inflammatory neutrophilic response leading to bronchiolitis and pneumonia.
Nagarjuna R. Cheemarla, Antonieta Guerrero-Plata   +1 more
doaj   +1 more source

A Re-emerging Respiratory Virus: Human Metapneumovirus (hMPV)

Cureus
Human metapneumovirus (hMPV) is identified as a pathogenic agent responsible for respiratory tract infections in paediatric, adult and elderly populations. It is a spherical, enveloped virus with a diameter of 209nm, consisting of a single-stranded, non-segmented, and negative-sense RNA genome of around 13.3 kb in length.
Mishra, Baijayantimala, Mohapatra, Diksha, Tripathy, Manisha, Mamidi, Prabhudutta, Mohapatra, Prasanta R   +4 more
openaire   +2 more sources

The impact of eliminating reserve requirements on US banks' lending, liquidity, and profitability during COVID‐19

Review of Financial Economics, Volume 44, Issue 1, January 2026.
Abstract The US Federal Reserve System (Fed) eliminated reserve requirements for banks in March 2020 during the first quarter of the COVID‐19 pandemic to foster bank lending through expansionary monetary policy. However, we find empirical evidence that the reserve requirements elimination was not able to support bank lending but instead increased the ...
Jascha‐Alexander Koch, Mohammad Saiful Islam   +1 more
wiley   +1 more source

Is Higher Viral Load in the Upper Respiratory Tract Associated With Severe Pneumonia? Findings From the PERCH Study. [PDF]

, 2017
BACKGROUND.: The etiologic inference of identifying a pathogen in the upper respiratory tract (URT) of children with pneumonia is unclear. To determine if viral load could provide evidence of causality of pneumonia, we compared viral load in the URT of ...
Adrian, Peter V, Antonio, Martin, Awori, Juliet O, Baggett, Henry C, Baillie, Vicky L, Brooks, W Abdullah, Deloria Knoll, Maria, DeLuca, Andrea N, Driscoll, Amanda J, Ebruke, Bernard E, Feikin, Daniel R, Fu, Wei, Goswami, Doli, Hammitt, Laura L, Higdon, Melissa M, Howie, Stephen RC, Karron, Ruth A, Kotloff, Karen L, Levine, Orin S, Li, Mengying, Madhi, Shabir A, Morpeth, Susan C, Murdoch, David R, Mwaba, John, Mwansa, James, O' Brien, Katherine L, Park, Daniel E, PERCH Study Group, Prosperi, Christine, Sawatwong, Pongpun, Scott, J Anthony G, Shi, Qiyuan, Sow, Samba O, Tapia, Milagritos D, Thea, Donald M, Whistler, Toni, Zaman, Khalequ, Zeger, Scott L   +37 more
core   +1 more source

Human Metapneumovirus Establishes Persistent Infection in Lung Microvascular Endothelial Cells and Primes a Th2-Skewed Immune Response

Microorganisms, 2020
Human Metapneumovirus (HMPV) is a major cause of lower respiratory tract infections. HMPV infection has been hypothesized to alter dendritic cell (DC) immune response; however, many questions regarding HMPV pathogenesis within the infected lung remain ...
Antonella Bugatti, Stefania Marsico, Manuela Fogli, Sara Roversi, Serena Messali, Daniela Bosisio, Cinzia Giagulli, Arnaldo Caruso, Silvano Sozzani, Simona Fiorentini, Francesca Caccuri   +10 more
doaj   +1 more source

A Sendai virus recombinant vaccine expressing a gene for truncated human metapneumovirus (hMPV) fusion protein protects cotton rats from hMPV challenge

Virology, 2017
Human metapneumovirus (hMPV) infections pose a serious health risk to young children, particularly in cases of premature birth. No licensed vaccine exists and there is no standard treatment for hMPV infections apart from supportive hospital care. We describe the production of a Sendai virus (SeV) recombinant that carries a gene for a truncated hMPV ...
Charles J, Russell, Bart G, Jones, Robert E, Sealy, Sherri L, Surman, John N, Mason, Randall T, Hayden, Ralph A, Tripp, Toru, Takimoto, Julia L, Hurwitz   +8 more
openaire   +2 more sources

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon, Merle Sophie Kaiser, Marcus Bachmann, Gérard Krause, Jens Gottlieb   +4 more
wiley   +1 more source

Epidemiology and Clinical Impact of Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
ABSTRACT Background Respiratory viral infections (RVIs) can have distinct clinical presentations and outcomes in non‐lung solid organ transplant (SOT) recipients compared to non‐transplant and lung transplant patients. Understanding their impact is crucial for improving patient care and outcomes.
Manon L. M. Prins, Ernst D. van Dokkum, Aiko P. J. de Vries, Maarten E. Tushuizen, Danny van der Helm, Edwin M. Spithoven, Irene M. van der Meer, Eduard M. Scholten, Albert M. Vollaard, Saskia le Cessie, Leo G. Visser, Geert H. Groeneveld   +11 more
wiley   +1 more source

Antigenic and genetic variability of human metapneumoviruses [PDF]

, 2004
Human metapneumovirus (HMPV) is a member of the subfamily Pneumovirinae within the family Paramyxo- viridae. Other members of this subfamily, respiratory syncytial virus and avian pneumovirus, can be divided into subgroups on the basis of genetic or ...
Cane, P.A., Forleo-Neto, E., Fouchier, R.A.M. (Ron), Herfst, S. (Sander), Hoogen, B.G. (Bernadette) van den, Osterhaus, A.D.M.E. (Albert), Sprong, L. (Leo), Swart, R.L. (Rik) de   +7 more
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