Results 71 to 80 of about 10,803 (226)

Distinguishing between recruitment and spread of silent chromatin structures in Saccharomyces cerevisiae

eLife, 2022
The formation of heterochromatin at HML, HMR, and telomeres in Saccharomyces cerevisiae involves two main steps: the recruitment of Sir proteins to silencers and their spread throughout the silenced domain.
Molly Brothers, Jasper Rine
doaj   +1 more source

Thin‐layer drying kinetics and mathematical modelling of osmotically pretreated vacuum dried green chilli

JSFA reports, EarlyView.
Abstract Background Chilli is highly perishable, often requiring drying to extend shelf life. This study assesses and compares the drying kinetics of osmotically pretreated green chilli under vacuum drying conditions while evaluating suitable mathematical models and calculating effective moisture diffusivity and activation energy. Results Sliced chilli
Md. Raihanul Haque, Md. Iftekhar Kabir, Md. Nahidul Islam, Md. Mojaffor Hosain, Md. Sazzat Hossain Sarker   +4 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Long term follow-up of drug resistant and drug susceptible tuberculosis contacts in a Low incidence setting

BMC Infectious Diseases, 2012
Background Studies examining the transmission of multidrug-resistant tuberculosis (MDR-TB) strains have yielded conflicting results. Methods We examined transmission of MDR-TB strains using contact tracing data from a low incidence setting.
Johnston James, Admon Andrew, Ibrahim Amir, Elwood Kevin, Tang Patrick, Cook Victoria, Fitzgerald Mark   +6 more
doaj   +1 more source

Chemoreactome analysis of 7-hydroxymatairesinol, 17-estradiol, phytoestrogen β-sitosterol and epigallocatechin-3-gallate

Акушерство, гинекология и репродукция, 2020
The results of the evaluation of 7-hydroximatairesinol (7-HMR) properties in comparison with control molecules (17-estradiol, phytoestrogen β-sytostirol, epigallocatechin-3-gallate) are presented.
I. Yu. Torshin, A. N. Rubashkina, N. P. Lapochkina, O. A. Gromova   +3 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Intraoperative hemodynamic imbalance quantification: clinical validation of heart rate to mean blood pressure ratio in predicting myocardial injury after noncardiac surgery

BMC Cardiovascular Disorders
Background The effects of isolated heart rate (HR) and mean blood pressure (MBP) on myocardial injury after noncardiac surgery (MINS) have been investigated, but the combined impact of intraoperative HR and MBP remains unclear. This study aimed to assess
Yuanjun Zhou, Weiming Chen, Fei Liang, Liping Zhong, Yilin Liao, Yuting Zhong   +5 more
doaj   +1 more source

Double Slag Operating Standard for Mitigation of CO2 Emissions in Basic Oxygen Steelmaking

steel research international, EarlyView.
Basic oxygen furnace (BOF) steelmaking uses a double slag process (DSP) to produce low‐phosphorus steel. To reduce carbon emissions in a BOF, the hot metal ratio (HMR) must be lowered. The present article describes the optimal conditions for DSP operations under low‐HMR conditions: temperature of 1360 ± 5 °C, total Fe content of 10 ± 2 wt%, basicity (=
Kyung Hwan Kim, Joo Hyun Park
wiley   +1 more source

Global distribution of aquatic animal telemetry effort reveals geographic biases and opportunities for more inclusive tracking studies

Conservation Science and Practice, EarlyView.
Despite broad global distribution of aquatic telemetry studies, important biogeographic regions remain poorly investigated. The most important variables correlated with the distribution of telemetry studies were political stability, conservation funding, number of scientific documents, and English as a first language.
S. T. Kessel, M. Auger‐Méthé, A. P. Barbosa Martins, S. J. Cooke, A. T. Fisk, A. L. Haley, M. R. Heupel, N. V. Klinard, J. K. Matley, M. L. Piczak, J. A. Robichaud, N. E. Hussey   +11 more
wiley   +1 more source

HMR localisation to repetitive elements.

, 2017
(A) HMR ChIP tag enrichment at repetitive DNA elements. To identify enriched sequences the enrichment (log2-fold) over input is plotted against the RPKM of an individual repeat sequence from RepBase.
Bo Sun (177052), Andrea Lukacs (3752956), Thomas Andreas Gerland (3752959), Andreas Walter Thomae (3752962), Pawel Smialowski (2947308), Axel Imhof (22181)   +5 more
core   +1 more source