Results 1 to 10 of about 1,032 (110)
Effect of institutional antimicrobial stewardship guidelines on prescription of critically important antimicrobials for dogs and cats [PDF]
Journal of Veterinary Internal MedicineBackground Veterinary hospital antimicrobial stewardship (AMS) guidelines might help combat antimicrobial resistance (AMR). Objectives Determine the conditions and types of infection for which antimicrobial drugs (AMDs) deemed critically important (CIA ...
Sarah N. Robbins +3 more
doaj +3 more sources
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics [PDF]
Nature Communications, 2021 Macrolides and ketolides comprise a family of clinically important antibiotics that inhibit protein synthesis by binding within the exit tunnel of the bacterial ribosome.
Bertrand Beckert +13 more
doaj +2 more sources
Antibiotic innovation may contribute to slowing the dissemination of multiresistant Streptococcus pneumoniae: the example of ketolides. [PDF]
PLoS ONE, 2008 BackgroundDespite increasingly frequent bacterial resistance to antibiotics, antibacterial innovation is rare. Ketolides constitute one of the very few new antibiotic classes active against Streptococcus pneumoniae developed during the last 25 years ...
Lulla Opatowski +6 more
doaj +1 more source
Results in Chemistry, 2023 Ketolides are the fourth generation semisynthetic macrolides derived from erythromycin A, designed to address the limitations of currently available drug treatments including penicillins, macrolides and glycopeptides.
Satish Bhavsar +10 more
doaj +1 more source
Emerging Treatment Options for Infections by Multidrug-Resistant Gram-Positive Microorganisms
Microorganisms, 2020 Antimicrobial agents are currently the mainstay of treatment for bacterial infections worldwide. However, due to the increased use of antimicrobials in both human and animal medicine, pathogens have now evolved to possess high levels of multi-drug ...
Despoina Koulenti +7 more
doaj +1 more source
Ceftiofur use and antimicrobial stewardship in the horse
Equine Veterinary Journal, Volume 55, Issue 6, Page 944-961, November 2023., 2023 Abstract Equine practitioners require recommendations that support antimicrobial stewardship and avoid generating resistance to medically important antibiotics. This review examines current inadequacies in antimicrobial stewardship standards within the veterinary community, related to antimicrobial categorisation and prescribing practices.
Clare A. Ryan +2 more
wiley +1 more source
Scaffold Modifications in Erythromycin Macrolide Antibiotics. A Chemical Minireview
Molecules, 2020 Clarithromycin and congeners are important antibacterial members of the erythromycin A 14-membered macrocyclic lactone family. The macrolide scaffold consists of a multifunctional core that carries both chemically reactive and non-reactive substituents ...
Kjell Undheim
doaj +1 more source
Antimicrobial prescribing and antimicrobial resistance surveillance in equine practice
Equine Veterinary Journal, Volume 55, Issue 3, Page 494-505, May 2023., 2023 Abstract Background Antimicrobial resistance (AMR) is an increasingly serious threat to human and animal health, therefore responsible use of antimicrobials in equine practice is vital. There is a need to have accurate, up to date data on antimicrobial prescribing in equine practice in the UK.
Amie Wilson +4 more
wiley +1 more source
A framework for evaluation of on‐farm mastitis diagnostics in Australia
Australian Veterinary Journal, Volume 101, Issue 4, Page 142-152, April 2023., 2023 Numerous culture‐based diagnostics are available on the Australian and international markets for on‐farm detection of bacterial pathogens in milk. Use of such diagnostics may provide an opportunity to improve the prudent use of antimicrobials in udder health management. Farms are low‐resource settings in terms of diagnostic microbiology capacity.
RN Zadoks +5 more
wiley +1 more source
Antibiotics, 2021 Lefamulin is the first of the pleuromutilin class of antimicrobials to be available for therapeutic use in humans. Minimum inhibitory concentrations of lefamulin were determined by microbroth dilution for 90 characterised clinical isolates (25 Ureaplasma
Oliver Spiller-Boulter +5 more
doaj +1 more source