Results 41 to 50 of about 1,296 (184)
APMIS, Volume 132, Issue 12, Page 1086-1095, December 2024.Azithromycin (AZM) is efficient for treatment of chronic Pseudomonas aeruginosa biofilm lung infections, despite of resistance in conventional susceptibility testing. It has been shown that planktonic P. aeruginosa are more susceptible to AZM when tested in RPMI 1640 medium. The aim of the study was to test the susceptibility to AZM of P.
Adrian Jimenez San San Mauro +2 more
wiley +1 more source
Current Perspectives on Treatment of Gram‐Positive Infections in India: What Is the Way Forward?
Interdisciplinary Perspectives on Infectious Diseases, Volume 2019, Issue 1, 2019., 2019 The emerging antimicrobial resistance leading to gram‐positive infections (GPIs) is one of the major public health threats worldwide. GPIs caused by multidrug resistant bacteria can result in increased morbidity and mortality rates along with escalated treatment cost and hospitalisation stay.
Atul P. Kulkarni +7 more
wiley +1 more source
Fundamental &Clinical Pharmacology, Volume 38, Issue 5, Page 988-997, October 2024.Abstract Background Hypersensitivity reactions (HSR) are reported for the macrolides, lincosamides, and streptogramins (MLS) antibiotic family. Data about cross‐reactivity among and between MLS remain scarce or controversial. Objectives The aim of this study was to provide an overview of hypersensitivity cross‐reactions among MLSs based on data ...
Quentin Le Baron +9 more
wiley +1 more source
EFSA Journal, Volume 15, Issue 10, October 2017., 2017 Abstract ECDC, EFSA and EMA have jointly established a list of harmonised outcome indicators to assist EU Member States in assessing their progress in reducing the use of antimicrobials and antimicrobial resistance (AMR) in both humans and food‐producing animals. The proposed indicators have been selected on the basis of data collected by Member States
ECDC +2 more
wiley +1 more source
, 2008 Ketolides differ from macrolides by removal of the 3-O-cladinose (replaced by a keto group), a 11,12- or 6,11-cyclic moiety and a heteroaryl-alkyl side chain attached to the macrocyclic ring through a suitable linker.
Joerg M Harms +9 more
core +1 more source
Telitromicine. A new therapeutic option from macrolides to ketolides.
Medisur, 2004 -
Pedro Miguel Milián Vázquez. +2 more
doaj +2 more sources
The antibiotic resistance crisis and the development of new antibiotics
Microbial Biotechnology, Volume 17, Issue 7, July 2024.The current Lilliput review analyses the question whether scientific or economic hurdles prevented the registration of new antibiotics. Scientifically, substantial progress has been achieved over recent years. The lack of profitability for costly novel antibiotic development necessitates push and pull efforts of the public sector to complement what the
Harald Brüssow
wiley +1 more source
, 2001 The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori .
I. Gustafsson +5 more
core +1 more source
In Vitro Activity of the Ketolide ABT-773 [PDF]
Antimicrobial Agents and Chemotherapy, 2001 ABSTRACT The in vitro activities of ABT-773, azithromycin, erythromycin, and clindamycin were compared by testing 1,223 clinical isolates selected to represent different species and phenotypes. ABT-773 was particularly potent against staphylococci (the MIC at which 90% of the strains tested were inhibited [MIC 90
A L, Barry, P C, Fuchs, S D, Brown
openaire +2 more sources