Results 41 to 50 of about 2,189 (196)
APMIS, Volume 132, Issue 12, Page 1086-1095, December 2024.Azithromycin (AZM) is efficient for treatment of chronic Pseudomonas aeruginosa biofilm lung infections, despite of resistance in conventional susceptibility testing. It has been shown that planktonic P. aeruginosa are more susceptible to AZM when tested in RPMI 1640 medium. The aim of the study was to test the susceptibility to AZM of P.
Adrian Jimenez San San Mauro +2 more
wiley +1 more source
Current Perspectives on Treatment of Gram‐Positive Infections in India: What Is the Way Forward?
Interdisciplinary Perspectives on Infectious Diseases, Volume 2019, Issue 1, 2019., 2019 The emerging antimicrobial resistance leading to gram‐positive infections (GPIs) is one of the major public health threats worldwide. GPIs caused by multidrug resistant bacteria can result in increased morbidity and mortality rates along with escalated treatment cost and hospitalisation stay.
Atul P. Kulkarni +7 more
wiley +1 more source
Telitromicine. A new therapeutic option from macrolides to ketolides.
Medisur, 2004 -
Pedro Miguel Milián Vázquez. +2 more
doaj +2 more sources
Fundamental &Clinical Pharmacology, Volume 38, Issue 5, Page 988-997, October 2024.Abstract Background Hypersensitivity reactions (HSR) are reported for the macrolides, lincosamides, and streptogramins (MLS) antibiotic family. Data about cross‐reactivity among and between MLS remain scarce or controversial. Objectives The aim of this study was to provide an overview of hypersensitivity cross‐reactions among MLSs based on data ...
Quentin Le Baron +9 more
wiley +1 more source
The antibiotic resistance crisis and the development of new antibiotics
Microbial Biotechnology, Volume 17, Issue 7, July 2024.The current Lilliput review analyses the question whether scientific or economic hurdles prevented the registration of new antibiotics. Scientifically, substantial progress has been achieved over recent years. The lack of profitability for costly novel antibiotic development necessitates push and pull efforts of the public sector to complement what the
Harald Brüssow
wiley +1 more source
South African actinobacteria: A treasure trove of novel bioactive metabolites for drug discovery
South African Journal of ScienceAlthough South Africa is known as one of the most biodiverse countries in the world, based on its unique plants and animals, microorganisms have received much less attention.
Kojo S. Acquah +2 more
doaj +1 more source
What is the role of microbial biotechnology and genetic engineering in medicine?
MicrobiologyOpen, Volume 13, Issue 2, April 2024.Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley +1 more source
Effects of EDP-420 on penicillin-resistant and quinolone- and penicillin-resistant pneumococci in the rabbit meningitis model [PDF]
, 2017 Objectives To test the efficacy of EDP-420, a new ketolide, in experimental pneumococcal meningitis and to determine its penetration into the CSF. Methods The experimental rabbit model was used in this study and EDP-420 was tested against a penicillin ...
Acosta, Fernando +9 more
core
The energy landscape of the ribosome
Biopolymers, Volume 115, Issue 2, March 2024.Abstract The ribosome is a prototypical assembly that can be used to establish general principles and techniques for the study of biological molecular machines. Motivated by the fact that the dynamics of every biomolecule is governed by an underlying energy landscape, there has been great interest to understand and quantify ribosome energetics.
Sandra Byju +2 more
wiley +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2009 BACKGROUND: The Canadian Ward Surveillance Study (CANWARD 2007) tested isolates collected from January to December 2007 from 12 Canadian hospitals to a range of antimicrobial agents.
Aleksandra K Wierzbowski +5 more
doaj +1 more source