Results 61 to 70 of about 1,296 (184)

Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives):  A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens

open access: yes, 2016
In the search for new antibiotics active against macrolide-resistant pneumococci and Haemophilus influenzae, we synthesized a new class of 3-oxo-6-O-methylerythromycin derivatives, so-called “ketolides”. A keto function was introduced in position 3 after
Arlette Dussarat (3022353)   +14 more
core   +1 more source

Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics

open access: yes, 2021
Ketolides, characterized by possessing a 3-keto group in place of the l-cladinose moiety of erythromycin A, are the recent generation of antimicrobials derived semi-synthetically from the 14-membered ring macrolide erythromycin A.
윤여준
core   +1 more source

Corrigendum to “Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction”

open access: yes, 2017
BioMed Research International, Volume 2017, Issue 1, 2017.
Ijaz Ahmad   +4 more
wiley   +1 more source

Erythromycin-induced insensitivity of coagulase-negative staphylococci to telithromycin

open access: yesCurrent Issues in Pharmacy and Medical Sciences
Telithromycin represents a new group of antibiotics, called ketolides, belonging to  the same family as MLSB (macrolide, lincosamide, streptogramin B) antibiotics.
Marek Juda   +5 more
doaj  

Opioid analgesics-related pharmacokinetic drug interactions: from the perspectives of evidence based on randomized controlled trials and clinical risk management

open access: yesJournal of Pain Research, 2017
Xiu-qin Feng,1 Ling-ling Zhu,2 Quan Zhou3 1Nursing Administration Office, Division of Nursing, 2VIP Care Ward, Division of Nursing, 3Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang ...
Feng XQ, Zhu LL, Zhou Q
doaj  

Antibiotic activity against naive and induced Streptococcus pneumoniae biofilms in an in vitro pharmacodynamic model

open access: yes, 2014
Biofilms play a role in the pathogenicity of pneumococcal infections. A pharmacodynamic in vitro model of biofilm was developed that allows characterization of the activity of antibiotics against viability and biomass by using in parallel capsulated ...
Van Bambeke, Françoise   +2 more
core   +1 more source

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