Evaluation of a FRET-peptide substrate to predict virulence in Pseudomonas aeruginosa [PDF]
, 2013 Pseudomonas aeruginosa produces a number of proteases that are associated with virulence and disease progression. A substrate able to detect P. aeruginosa-specific proteolytic activity could help to rapidly alert clinicians to the virulence potential of ...
Alex Van Belkum +7 more
core +7 more sources
Mycoplasma pneumoniae in community acquired pneumonias [PDF]
, 2005 Mycoplasma pneumoniae is best thought of as a bacterium without a cell wall, a property that has important therapeutic considerations. It is an exclusively human pathogen. As most cases of human infection are either sub clinical or result in a relatively
Caruana, Paul
core
Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation [PDF]
, 2015 Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide antibiotics display well described immunomodulatory properties, presumably involved in their clinical ...
Gualdoni, Guido A. +5 more
core +1 more source
"In vitro" activities of antimycobacterial agents against Mycobacterium avium subsp. paratuberculosis linked to Crohn's disease and paratuberculosis [PDF]
, 2006 Crohn's disease, a human disease similar to paratuberculosis in animals is the most painful and devastating disease that may involve infection with M. avium subsp.
Ahmed, Niyaz +5 more
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Antibiotics for exacerbations of asthma. [PDF]
, 2018 BACKGROUND: Asthma is a chronic respiratory condition that affects over 300 million adults and children worldwide. It is characterised by wheeze, cough, chest tightness, and shortness of breath.
Del Forno, M +5 more
core +1 more source
, 2017 BioMed Research International, Volume 2017, Issue 1, 2017.
Ijaz Ahmad +4 more
wiley +1 more source
Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs [PDF]
, 2013 Rates of infection with antibiotic-resistant bacteria have increased precipitously over the past several decades, with far-reaching healthcare and societal costs.
Ahmadi, Sara +4 more
core +2 more sources
Macròlids: mecanismes d'acció i de resistència [PDF]
, 2005 Els macròlids són agents descrits per primera vegada als anys cinquanta, molt emprats en el tractament de microorganismes grampositius. Actuen al ribosoma, unint-se de manera reversible a la subunitat 50S. Actualment se'n coneixen diferents mecanismes de
Portillo, Aránzazu +2 more
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The combined effects of pH and acetonitrile composition on the separation of two lincosamide antibiotics [PDF]
, 2014 Objective: Reversed-phase chromatography has become the method of choice to separate compounds that are similar in structure to each other. Selectivity, resolution and retention time can be improved by controlling different variants.
Azzopardi, Lilian M. +6 more
core +2 more sources
Long-term azithromycin therapy in patients with severe chronic obstructive pulmonary disease and repeated pulmonary exacerbations [PDF]
, 2012 L'objectiu es determinar si el tractament amb azitromicina a llarg termini redueix la freqüència d'exacerbacions respiratòries en pacients amb malaltia pulmonar obstructiva crònica (MPOC) greu.
Montón Soler, Conchita +4 more
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