Results 61 to 70 of about 12,842 (224)

Immune cell-lipoprotein imbalance as a marker for early diagnosis of non-small cell lung cancer metastasis

open access: yesFrontiers in Oncology, 2022
The underlying molecular mechanisms and evolutionary patterns of lung cancer metastasis remain unclear, resulting in a lack of effective indicators for early diagnosis of metastasis.
Wei Zhang   +9 more
doaj   +1 more source

Long-Range Communication between the Silencers of HMR [PDF]

open access: yesMolecular and Cellular Biology, 2008
Gene regulation involves long-range communication between silencers, enhancers, and promoters. In Saccharomyces cerevisiae, silencers flank transcriptionally repressed genes to mediate regional silencing. Silencers recruit the Sir proteins, which then spread along chromatin to encompass the entire silenced domain.
Lourdes, Valenzuela   +4 more
openaire   +2 more sources

Genome of Cupriavidus sp. HMR-1, a Heavy Metal-Resistant Bacterium

open access: yesGenome Announcements, 2013
Cupriavidus sp. HMR-1 was isolated from a heavy metal-enriched culture of activated sludge from a wastewater treatment plant in Hong Kong. Here, we release the HMR-1 genome to provide basic genetic characteristics for a better understanding of its ...
Li-Guan Li, Lin Cai, Tong Zhang
semanticscholar   +1 more source

Pesticide MRLs as Trade Barriers: Evidence From Vietnam's Coffee and Rice Exporters

open access: yesAgribusiness, EarlyView.
ABSTRACT As tariffs have declined globally through bilateral and regional trade agreements, food safety standards have emerged as significant determinants of agricultural trade flows. This study examines the impact of maximum residue limits (MRLs) for five pesticides—Azoxystrobin, Chlorpyrifos, Chlorantraniliprole, Clothianidin, and Cyhalothrin—on ...
Nhat Mai Nguyen   +2 more
wiley   +1 more source

HMR-I Is an Origin of Replication and a Silencer in Saccharomyces cerevisiae [PDF]

open access: yesGenetics, 1999
Abstract There appear to be fundamental differences between the properties of the silencers at HML and HMR, with some being origins of replication and others not. Moreover, past studies have suggested that HMR-I's role in silencing may be restricted to plasmid contexts.
D H, Rivier, J L, Ekena, J, Rine
openaire   +2 more sources

Informing policy makers in developing countries: Practices and limitations of geriatric home medication review in Malaysia-A qualitative inquiry

open access: yesAsian Pacific Journal of Tropical Medicine
Objective: To explore existing practices and challenges in the delivery of geriatric home medication review (HMR). The study was part of a larger study aimed to offer solution to expand the range of geriatric HMR. Methods: This study employed qualitative
Ahlam Sundus   +2 more
doaj   +1 more source

Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva   +12 more
doaj   +1 more source

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn   +10 more
wiley   +1 more source

In Vitro Pharmacodynamic Studies of Activities of Ketolides HMR 3647 (Telithromycin) and HMR 3004 against Extracellular or Intracellular Helicobacter pylori [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2001
ABSTRACT The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori . Both ketolides showed a pronounced concentration-dependent killing, a significant postantibiotic effect, a long postantibiotic sub-MIC effect, and a reduction of ...
I, Gustafsson, L, Engstrand, O, Cars
openaire   +2 more sources

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

open access: yesChemistry – A European Journal, EarlyView.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn   +5 more
wiley   +1 more source

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