Results 91 to 100 of about 12,842 (224)

Hemoglobin-to-RDW ratio, hemoglobin-to-monocyte ratio, and hemoglobin-to-leukocyte ratio are predictive of 14-day readmission after primary total knee arthroplasty

open access: yesJournal of Orthopaedic Surgery and Research
Background Total knee arthroplasty (TKA) is an effective treatment for knee osteoarthritis; however, early readmissions due to complications are common.
Ngi-Chiong Lau   +4 more
doaj   +1 more source

Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model

open access: yesStem Cells International, 2019
Mucopolysaccharidosis type 1 (MPS-1), also known as Hurler’s disease, is a congenital metabolic disorder caused by a mutation in the alpha-L-iduronidase (IDUA) gene, which results in the loss of lysosomal enzyme function for the degradation of ...
Toshio Miki   +6 more
doaj   +1 more source

First Attempt to Estimate a Joint Distribution for Income and Wealth Within the Distributional National Accounts Framework

open access: yesReview of Income and Wealth, Volume 72, Issue 3, August 2026.
ABSTRACT Over recent years, there have been several projects to include distributional aspects in the national accounts' framework. Household distributional information will also be covered in the 2025 SNA. Additionally, increasing emphasis has been placed on covering all material aspects of welfare at the macro as well as micro level in the same macro
Nina Blatnik   +2 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1305-1313, July 2026.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

open access: yesAdvanced Science, Volume 13, Issue 38, 9 July 2026.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao   +8 more
wiley   +1 more source

A pharmacist-led intervention for increasing the uptake of Home Medicines Review (HMR) among residents of retirement villages (PHARMER): protocol for a cluster randomised controlled trial

open access: yesBMC Health Services Research, 2011
Background The majority of retirement village residents are at risk of medication misadventure. In a recent survey of retirement village residents in Victoria, two-thirds had at least one medication-related risk factor, and hence were eligible to receive
Elliott Rohan A   +3 more
doaj   +1 more source

Novel heavy metal resistance gene clusters are present in the genome of Cupriavidus neocaledonicus STM 6070, a new species of Mimosa pudica microsymbiont isolated from heavy-metal-rich mining site soil

open access: yesBMC Genomics, 2020
Background Cupriavidus strain STM 6070 was isolated from nickel-rich soil collected near Koniambo massif, New Caledonia, using the invasive legume trap host Mimosa pudica.
Agnieszka Klonowska   +14 more
doaj   +1 more source

Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population‐Based Study

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1414-1424, July 2026.
Objective To assess the association between early antimalarial adherence and future acute care utilization and cost in a population‐based cohort of incident rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Methods All patients with incident RA/SLE and new antimalarial use in British Columbia, Canada, between January 1997 and March 2022
Md Rashedul Hoque   +7 more
wiley   +1 more source

Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast.

open access: yesGenes & Development, 1995
RAP1 is a sequence-specific DNA-binding protein in yeast that can either repress or activate transcription. Previous studies have demonstrated a direct role for RAP1 in silencing at HM mating-type loci and telomeres.
Stephen W. Buck, David Shore
semanticscholar   +1 more source

Co‐design–related approaches in medication safety for people with dementia: A scoping review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2005-2015, July 2026.
Background People with dementia manage complex medication regimens and face a heightened risk of medication‐related harm. Co‐design approaches are increasingly being used to develop interventions/tools to improve medication safety in this population. Objectives To describe how co‐design has been applied in developing interventions or tools related to ...
Zena El‐kadomi   +3 more
wiley   +1 more source

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