Results 91 to 100 of about 10,803 (226)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1305-1313, July 2026.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Relationship between FFR, CFR and (BMR/HMR).

open access: yes, 2019
CFR and FFR are related through the ratio of basal to hyperemic vascular resistances (BMR / HMR); see Eq (6). The dot colors represent the measured BMR-over-HMR ratios.
Mauro Echavarria-Pinto (6181274)   +8 more
core   +1 more source

Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model

open access: yesStem Cells International, 2019
Mucopolysaccharidosis type 1 (MPS-1), also known as Hurler’s disease, is a congenital metabolic disorder caused by a mutation in the alpha-L-iduronidase (IDUA) gene, which results in the loss of lysosomal enzyme function for the degradation of ...
Toshio Miki   +6 more
doaj   +1 more source

Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population‐Based Study

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1414-1424, July 2026.
Objective To assess the association between early antimalarial adherence and future acute care utilization and cost in a population‐based cohort of incident rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Methods All patients with incident RA/SLE and new antimalarial use in British Columbia, Canada, between January 1997 and March 2022
Md Rashedul Hoque   +7 more
wiley   +1 more source

A pharmacist-led intervention for increasing the uptake of Home Medicines Review (HMR) among residents of retirement villages (PHARMER): protocol for a cluster randomised controlled trial

open access: yesBMC Health Services Research, 2011
Background The majority of retirement village residents are at risk of medication misadventure. In a recent survey of retirement village residents in Victoria, two-thirds had at least one medication-related risk factor, and hence were eligible to receive
Elliott Rohan A   +3 more
doaj   +1 more source

Co‐design–related approaches in medication safety for people with dementia: A scoping review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2005-2015, July 2026.
Background People with dementia manage complex medication regimens and face a heightened risk of medication‐related harm. Co‐design approaches are increasingly being used to develop interventions/tools to improve medication safety in this population. Objectives To describe how co‐design has been applied in developing interventions or tools related to ...
Zena El‐kadomi   +3 more
wiley   +1 more source

Novel heavy metal resistance gene clusters are present in the genome of Cupriavidus neocaledonicus STM 6070, a new species of Mimosa pudica microsymbiont isolated from heavy-metal-rich mining site soil

open access: yesBMC Genomics, 2020
Background Cupriavidus strain STM 6070 was isolated from nickel-rich soil collected near Koniambo massif, New Caledonia, using the invasive legume trap host Mimosa pudica.
Agnieszka Klonowska   +14 more
doaj   +1 more source

Robotic‐Assisted Electrode Array Insertion Improves Stability of Acoustic Hearing Thresholds

open access: yesThe Laryngoscope, Volume 136, Issue 7, Page 3146-3154, July 2026.
This study evaluated the impact of robotic‐assisted electrode array insertion on rates of delayed‐onset hearing loss (DOHL). DOHL occurred in 22 of 60 subjects (37%) in the manual cohort compared with 2 of 29 subjects (7%) in the robotic‐assisted cohort, representing a statistically significant reduction (p = 0.002).
Uzair A. Khan   +7 more
wiley   +1 more source

Uncertainty in aquatic greenhouse gas flux estimates arises from subjective processing of floating chamber time series

open access: yesLimnology and Oceanography: Methods, Volume 24, Issue 7, July 2026.
Abstract Accurate quantification of greenhouse gas (GHG) fluxes from aquatic systems is essential for constraining regional and global carbon budgets. Closed floating chambers are widely used to measure carbon dioxide (CO2) and methane (CH4) fluxes at the water–air interface, yet large uncertainties persist due to subjective processing of chamber time ...
Camille Minaudo   +16 more
wiley   +1 more source

Expression of hMR in vaginal cells.

open access: yes, 2013
(a) Purity of vaginal epithelial cells: RT-PCR for lymphocyte marker CD3 (lane 2, 5 9), macrophage/monocyte marker CD14 (lanes 3, 6, 10) and dendritic cell marker CD11c (lanes 4, 7 and 11) using RNA isolated form PBMCs (lane 2, 3, 4), epithelial cells ...
Deepak N. Modi (336287)   +3 more
core   +1 more source

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