Background Establishment of DNA methylation (DNAme) patterns is essential for balanced multi-lineage cellular differentiation, but exactly how these patterns drive cellular phenotypes is unclear.
Timothy J. Scott +3 more
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Antimicrobial Activity of Hydroxymatairesinol (HMR) Lignan
Lignans are natural products widely distributed in the plant kingdom. They are composed of two β-β-linked phenylpropane (shikimate-derived biogenetic subunits). Although the backbone of lignans is composed of phenylpropane units, there is enormous diversity in the structure of lignans leading to different classes of lignans, such as γ-butyrolactone ...
Widad M.K. Al-Ani, Fitua M. Aziz
openaire +3 more sources
In Vitro Pharmacodynamics of the New Ketolides HMR 3004 and HMR 3647 (Telithromycin) against Chlamydia pneumoniae [PDF]
ABSTRACT The ketolides HMR 3004 and HMR 3647 (telithromycin) are a new class of macrolides that have a potential clinical efficacy against intracellular pathogens. The objectives of this study were to investigate the MIC, minimum bactericidal concentration, and time-dependent killing of two Chlamydia pneumoniae
I, Gustafsson, E, Hjelm, O, Cars
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HIV gp120 binds to mannose receptor on vaginal epithelial cells and induces production of matrix metalloproteinases. [PDF]
BACKGROUND: During sexual transmission of HIV in women, the virus breaches the multi-layered CD4 negative stratified squamous epithelial barrier of the vagina, to infect the sub-epithelial CD4 positive immune cells.
Sashaina E Fanibunda +3 more
doaj +1 more source
Abalone (Haliotis discus hannai) has high nutritional value and market demand. However, it is generally sold as a raw product, which suffers from lengthy preparation, low commercial value, and a short shelf life.
Bertoka Fajar Surya Perwira Negara +4 more
doaj +1 more source
The Hmr and Lhr hybrid incompatibility genes suppress a broad range of heterochromatic repeats. [PDF]
Hybrid incompatibilities (HIs) cause reproductive isolation between species and thus contribute to speciation. Several HI genes encode adaptively evolving proteins that localize to or interact with heterochromatin, suggesting that HIs may result from co ...
P R V Satyaki +8 more
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In vitro activity of ketolides HMR 3004 and HMR 3647 and seven other antimicrobial agents against Corynebacterium diphtheriae [PDF]
The in vitro activities of two ketolides, HMR 3004 and HMR 3647 (telithromycin), and the comparator agents erythromycin A, azithromycin, clarithromycin, roxithromycin, levofloxacin, ofloxacin and penicillin G were determined by an agar dilution method against 410 isolates of Corynebacterium diphtheriae.
K H, Engler, M, Warner, R C, George
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The ketolide antibiotics HMR 3647 and HMR 3004 are active against Toxoplasma gondii in vitro and in murine models of infection [PDF]
Ketolides are a new class of macrolide antibiotics that have been shown to be active against a variety of bacteria including macrolide-resistant bacteria and mycobacteria. We examined two ketolides, HMR 3647 and HMR 3004, for their in vitro and in vivo activities against the protozoan parasite Toxoplasma gondii.
F G, Araujo +4 more
openaire +2 more sources
We propose a position control method for a helical magnetic robot (HMR) that uses the rotating frequency of the external rotating magnetic field (ERMF) to minimize the position fluctuation of the HMR caused by pulsatile flow in human blood vessels.
Jongyul Kim +4 more
doaj +1 more source
Tracking Australian health and medical research expenditure with a PubMed bibliometric method
Objective: To assess Australian health and medical research (HMR) investment returns by measuring the trends in HMR expenditure and PubMed publications by Australian authors. Methods: Bibliometric analysis collating Australian HMR expenditure reported by
Kumara Mendis +2 more
doaj +1 more source

