Results 71 to 80 of about 12,123 (240)

Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices

Frontiers in Cardiovascular Medicine, 2022
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva, Luis Paiva, Luis Paiva, Luis Paiva, Rogério Teixeira, Rogério Teixeira, Rogério Teixeira, Maria João Ferreira, Maria João Ferreira, Maria João Ferreira, Lino Gonçalves, Lino Gonçalves, Lino Gonçalves   +12 more
doaj   +1 more source

Long-Range Communication between the Silencers of HMR [PDF]

Molecular and Cellular Biology, 2008
Gene regulation involves long-range communication between silencers, enhancers, and promoters. In Saccharomyces cerevisiae, silencers flank transcriptionally repressed genes to mediate regional silencing. Silencers recruit the Sir proteins, which then spread along chromatin to encompass the entire silenced domain.
Lourdes, Valenzuela, Namrita, Dhillon, Rudra N, Dubey, Marc R, Gartenberg, Rohinton T, Kamakaka   +4 more
openaire   +2 more sources

In Vitro Pharmacodynamic Studies of Activities of Ketolides HMR 3647 (Telithromycin) and HMR 3004 against Extracellular or Intracellular Helicobacter pylori [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori . Both ketolides showed a pronounced concentration-dependent killing, a significant postantibiotic effect, a long postantibiotic sub-MIC effect, and a reduction of ...
I, Gustafsson, L, Engstrand, O, Cars
openaire   +2 more sources

Chemoreactome analysis of 7-hydroxymatairesinol, 17-estradiol, phytoestrogen β-sitosterol and epigallocatechin-3-gallate

Акушерство, гинекология и репродукция, 2020
The results of the evaluation of 7-hydroximatairesinol (7-HMR) properties in comparison with control molecules (17-estradiol, phytoestrogen β-sytostirol, epigallocatechin-3-gallate) are presented.
I. Yu. Torshin, A. N. Rubashkina, N. P. Lapochkina, O. A. Gromova   +3 more
doaj   +1 more source

The HMR C-terminus is required for HMR localization in proximity to centromeres and HP1a-bound chromatin (related to Fig 4).

, 2021
(A) Heatmaps of ChIP-seq profiles (z-score normalized) centred at high confidence FLAG-HMR peaks in 4 kb windows. Peaks are grouped by HP1a class and sorted by the ChIP signal in native HMR ChIP.
Natalia Y. Kochanova (11320681), Peter Krueger (11320675), Wasim Aftab (11320684), Anuroop V. Venkatasubramani (11320678), Andrea Lukacs (3752956), Andreas W. Thomae (11320672), Ignasi Forne (11320690), Tamas Schauer (740869), Rupam Choudhury (11320687), Axel Imhof (22181)   +9 more
core   +1 more source

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Frontiers in Genetics
BackgroundMultiple myeloma (MM) is an incurable plasma cell malignancy with high heterogeneity. Current staging systems, including the International Staging System (ISS) and Revised ISS (R-ISS), have limited prognostic accuracy. Given the role of histone
Juan Lyu, Shanmei Lyu, Ying Qian, Yi Feng, Zhuan Zheng, Lihong Zhang   +5 more
doaj   +1 more source

Implementation of the Goal-directed Medication review Electronic Decision Support System (G-MEDSS)© into home medicines review: a protocol for a cluster-randomised clinical trial in older adults

BMC Geriatrics, 2020
Background Older people living in the community have a high prevalence of polypharmacy and are vulnerable to adverse drug events. Home Medicines Review (HMR) is a collaborative medication review service involving general practitioners (GPs), accredited ...
Lisa Kouladjian O’Donnell, Mouna Sawan, Emily Reeve, Danijela Gnjidic, Timothy F. Chen, Patrick J. Kelly, J. Simon Bell, Sarah N. Hilmer   +7 more
doaj   +1 more source

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

Carbon Energy, EarlyView.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie, Jia Ouyang, Manu Suvarna, Xiangzhou Yuan, Matthew R. Hill, Uwe Bornscheuer, Huiyan Zhang, Yong Sik Ok   +7 more
wiley   +1 more source

Long term follow-up of drug resistant and drug susceptible tuberculosis contacts in a Low incidence setting

BMC Infectious Diseases, 2012
Background Studies examining the transmission of multidrug-resistant tuberculosis (MDR-TB) strains have yielded conflicting results. Methods We examined transmission of MDR-TB strains using contact tracing data from a low incidence setting.
Johnston James, Admon Andrew, Ibrahim Amir, Elwood Kevin, Tang Patrick, Cook Victoria, Fitzgerald Mark   +6 more
doaj   +1 more source

HMR localization in different ovarial cell types.

, 2021
Representative images of the germarium (A), Stage 3 oocytes (B), Stage 3 nurse cells (C) and different stages of follicle cells (D) from D. melanogaster ovarioles.
Natalia Y. Kochanova (11320681), Peter Krueger (11320675), Wasim Aftab (11320684), Anuroop V. Venkatasubramani (11320678), Andrea Lukacs (3752956), Andreas W. Thomae (11320672), Ignasi Forne (11320690), Tamas Schauer (740869), Rupam Choudhury (11320687), Axel Imhof (22181)   +9 more
core   +1 more source