Results 61 to 70 of about 9,042 (190)

Timing of Work‐Rest Implementation Influences Worker Productivity Under Heat Stress: Evidence for Initial Stay Time‐Based Scheduling

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Work‐rest allocations recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) limit heat strain and are typically implemented from the onset of work. Whether delaying implementation until after the initial stay time (IST; the duration of continuous work before core temperature reaches 38.0°C) improves ...
Glen P. Kenny, Kelli E. McCormick, Katie E. Wagar, Roberto C. Harris‐Mostert, James J. McCormick, Leonidas G. Ioannou, Fergus K. O'Connor   +6 more
wiley   +1 more source

Long-Range Communication between the Silencers of HMR [PDF]

Molecular and Cellular Biology, 2008
Gene regulation involves long-range communication between silencers, enhancers, and promoters. In Saccharomyces cerevisiae, silencers flank transcriptionally repressed genes to mediate regional silencing. Silencers recruit the Sir proteins, which then spread along chromatin to encompass the entire silenced domain.
Lourdes, Valenzuela, Namrita, Dhillon, Rudra N, Dubey, Marc R, Gartenberg, Rohinton T, Kamakaka   +4 more
openaire   +2 more sources

Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices

Frontiers in Cardiovascular Medicine, 2022
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva, Luis Paiva, Luis Paiva, Luis Paiva, Rogério Teixeira, Rogério Teixeira, Rogério Teixeira, Maria João Ferreira, Maria João Ferreira, Maria João Ferreira, Lino Gonçalves, Lino Gonçalves, Lino Gonçalves   +12 more
doaj   +1 more source

In Vitro Pharmacodynamic Studies of Activities of Ketolides HMR 3647 (Telithromycin) and HMR 3004 against Extracellular or Intracellular Helicobacter pylori [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori . Both ketolides showed a pronounced concentration-dependent killing, a significant postantibiotic effect, a long postantibiotic sub-MIC effect, and a reduction of ...
I, Gustafsson, L, Engstrand, O, Cars
openaire   +2 more sources

Immune cell-lipoprotein imbalance as a marker for early diagnosis of non-small cell lung cancer metastasis

Frontiers in Oncology, 2022
The underlying molecular mechanisms and evolutionary patterns of lung cancer metastasis remain unclear, resulting in a lack of effective indicators for early diagnosis of metastasis.
Wei Zhang, Weiwei Wang, Weiwei Wang, Junlu Wu, Jiale Tian, Wenhui Yan, Yi Yuan, Yiwen Yao, Anquan Shang, Wenqiang Quan   +9 more
doaj   +1 more source

Implementation of the Goal-directed Medication review Electronic Decision Support System (G-MEDSS)© into home medicines review: a protocol for a cluster-randomised clinical trial in older adults

BMC Geriatrics, 2020
Background Older people living in the community have a high prevalence of polypharmacy and are vulnerable to adverse drug events. Home Medicines Review (HMR) is a collaborative medication review service involving general practitioners (GPs), accredited ...
Lisa Kouladjian O’Donnell, Mouna Sawan, Emily Reeve, Danijela Gnjidic, Timothy F. Chen, Patrick J. Kelly, J. Simon Bell, Sarah N. Hilmer   +7 more
doaj   +1 more source

Chemoreactome analysis of 7-hydroxymatairesinol, 17-estradiol, phytoestrogen β-sitosterol and epigallocatechin-3-gallate

Акушерство, гинекология и репродукция, 2020
The results of the evaluation of 7-hydroximatairesinol (7-HMR) properties in comparison with control molecules (17-estradiol, phytoestrogen β-sytostirol, epigallocatechin-3-gallate) are presented.
I. Yu. Torshin, A. N. Rubashkina, N. P. Lapochkina, O. A. Gromova   +3 more
doaj   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

Chemistry – A European Journal, EarlyView.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn, Susanne Gradl, Vanessa Osterloh, Peter Gmeiner, Harald Hübner, Markus R. Heinrich   +5 more
wiley   +1 more source

Intraoperative hemodynamic imbalance quantification: clinical validation of heart rate to mean blood pressure ratio in predicting myocardial injury after noncardiac surgery

BMC Cardiovascular Disorders
Background The effects of isolated heart rate (HR) and mean blood pressure (MBP) on myocardial injury after noncardiac surgery (MINS) have been investigated, but the combined impact of intraoperative HR and MBP remains unclear. This study aimed to assess
Yuanjun Zhou, Weiming Chen, Fei Liang, Liping Zhong, Yilin Liao, Yuting Zhong   +5 more
doaj   +1 more source

Long term follow-up of drug resistant and drug susceptible tuberculosis contacts in a Low incidence setting

BMC Infectious Diseases, 2012
Background Studies examining the transmission of multidrug-resistant tuberculosis (MDR-TB) strains have yielded conflicting results. Methods We examined transmission of MDR-TB strains using contact tracing data from a low incidence setting.
Johnston James, Admon Andrew, Ibrahim Amir, Elwood Kevin, Tang Patrick, Cook Victoria, Fitzgerald Mark   +6 more
doaj   +1 more source