Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma [PDF]
BackgroundMultiple myeloma (MM) is an incurable plasma cell malignancy with high heterogeneity. Current staging systems, including the International Staging System (ISS) and Revised ISS (R-ISS), have limited prognostic accuracy. Given the role of histone
Juan Lyu +5 more
doaj +2 more sources
Drugs of the 21st century: telithromycin (HMR 3647)--the first ketolide [PDF]
Telithromycin (HMR 3647) is the first ketolide introduced into clinical practice. Ketolides are semisynthetic derivates of erythromycin A that carry novel biological properties on the erythronolide A ring. This new class of antimicrobials was designed to overcome current resistance mechanisms against erythromycin A within Gram-positive cocci. Ketolides
Grit, Ackermann, Arne C, Rodloff
openaire +3 more sources
Human and zebrafish mineralocorticoid receptors reporter cell assays to assess the activity of chemicals [PDF]
Summary: The action of environmental chemicals (ECs) on the mineralocorticoid receptor (MR) has been suggested to impair physiological processes regulated by this nuclear receptor. However, it remains understudied both as a target of ECs and with respect
Anna Toso +9 more
doaj +2 more sources
Polysaccharides from Citrus Fruit with Different Mastication Traits Ameliorate DSS-Induced Ulcerative Colitis by Restoring Intestinal Barrier Function and Microbiota Balance [PDF]
Mastication trait is an important indicator for evaluating citrus fruit texture and may modulate the biological activity of citrus polysaccharides.
Jieqiong Yao, Siyi Pan
doaj +2 more sources
Problems Encountered in Analyzing the Market Size, Purchase, and Consumption of HMR in the Republic of Korea [PDF]
Objectives: This study examined the problems encountered when analyzing the market size, purchase, and consumption of HMR (home meal replacements) in the Republic of Korea. Methods: The macro data relevant to the market size and purchase status of HMR
Sung Ok Kwon +3 more
doaj +1 more source
PC-HMR: Pose Calibration for 3D Human Mesh Recovery from 2D Images/Videos [PDF]
The end-to-end Human Mesh Recovery (HMR) approach has been successfully used for 3D body reconstruction. However, most HMR-based frameworks reconstruct human body by directly learning mesh parameters from images or videos, while lacking explicit guidance
Tianyu Luan +5 more
semanticscholar +1 more source
Applying Deep Learning-Based Human Motion Recognition System in Sports Competition
The exploration here intends to compensate for the traditional human motion recognition (HMR) systems' poor performance on large-scale datasets and micromotions.
Liangliang Zhang
doaj +1 more source
The silenced HMR domain is restricted from spreading by barrier elements, and the right barrier is a unique t-RNA(THR) gene. We show that sequences immediately flanking the silenced domain were enriched in acetylated, but not methylated, histones, whereas the barrier element was associated with a nucleosome-free region.
Oki, Masaya, Kamakaka, Rohinton T.
openaire +2 more sources

