Effect of Proinflammatory Cytokines on the Interplay between Roxithromycin, HMR 3647, or HMR 3004 and Human Polymorphonuclear Neutrophils [PDF]
ABSTRACTCytokines, the hallmarks of infectious and inflammatory diseases, modify phagocyte activities and thus may interfere with the immunomodulating properties of antibacterial agents. We have investigated whether various proinflammatory cytokines (interleukin 1 [IL-1], IL-6, IL-8, gamma interferon, tumor necrosis factor alpha [TNF-α], and ...
D, Vazifeh, A, Bryskier, M T, Labro
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(A) Recombinantly co-expressed HMRdC and LHR do not interact. Western blot showing anti-HA immunoprecipitation in nuclear extracts from Sf21 insect cells transfected with HA-HMR and His-LHR. IP performed with anti-HA antibody and western blot probed with
Natalia Y. Kochanova (11320681) +9 more
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Two different Hmr mutations interfere differently with HMR interactome and HMR complex formation.
Effect of Hmr2-tg (A) and HmrdC-tg (C) mutations on the HMR interaction with the HMR complex components and HP1a. Y-axis represents the Log2 fold-change of HMR2-tg/HMRwt-tg and HMRdC-tg/HMRwt-tg, respectively, calculated after normalization of each ...
Natalia Y. Kochanova (11320681) +9 more
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Bronchopulmonary Disposition of the Ketolide Telithromycin (HMR 3647) [PDF]
ABSTRACT Telithromycin (HMR 3647) is the first member of a new family of antimicrobials, the ketolides, developed specifically for the treatment of community-acquired respiratory tract infections. Telithromycin has proven in vitro activity against both common and atypical respiratory tract pathogens.
C, Muller-Serieys +6 more
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This study aims to explore the future development path of the college health education and health education's impact on students' sports exercise. Specifically, artificial intelligence (AI) algorithm is combined with intelligent robotics technology to ...
Minwei Chen, Yunzheng Zhou
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The database includes the raw data of the article “Neuroprotective effects of lignan 7-hydroxymatairesinol (HMR/lignan) in a rodent model of Parkinson’s disease” (doi.org/10.1016/j.nut.2019.04.006).
Pacchetti Barbara +7 more
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The bactericidal activities of HMR 3004, HMR 3647 and erythromycin against Gram-positive bacilli and development of resistance [PDF]
The bactericidal activities of two new ketolides, HMR 3004 and HMR 3647, and the potential to develop resistance to these two antibiotics were studied in Gram-positive bacilli. As judged by time-kill kinetics both ketolides were mostly bacteriostatic, being bactericidal against only highly susceptible isolates of Corynebacterium striatum (two isolates)
R, Fernández-Roblas +4 more
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The HMR C-terminus is required for HMR physiological function in D. melanogaster.
(A) Schematic representation of Hmr genotype in fly stocks used for complementation assays. Hmr null mutants (Df(1)Hmr -, here referred to as Hmrko) are complemented with wild type (Hmr+) or mutant (HmrdC and Hmr2) transgenic alleles inserted in the 3rd ...
Natalia Y. Kochanova (11320681) +9 more
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Maternal home meal replacement use and attitudes, and young children’s preferences by usage frequency in meals for young children: a cross-sectional study [PDF]
Objectives With the increase in women’s workforce participation and changing family eating habits, home meal replacements (HMRs) have become more prevalent.
Bo-Yeon Kim, Mi-Hyun Kim, Jee-Young Yeon
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The hybrid incompatibility proteins HMR and LHR interact in a defined HMR/LHR complex.
(A) and (B) Volcano plots highlighting reproducible interactors of HMR and LHR. Interactors consistently found in both HMR and LHR AP-MS are labelled in red.
Natalia Y. Kochanova (11320681) +9 more
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