Results 41 to 50 of about 87,902 (279)
Ecotoxicology and Environmental Safety, 2021 Heavy metals (HMs) contamination in agricultural soils is a major concern for global food safety and human health. Although, various in-situ and ex-situ remediation methods have been used for the treatment of HMs contaminated soils, however, they also ...
Temoor Ahmed +10 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018 Introduction The objective of the study is to validate attention and memory tasks that elicit event‐related potentials (ERPs) for utility as sensitive biomarkers for early dementia.
Shani Waninger +8 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Exome Sequencing in Saudi Arabian Pediatric Kidney Disease Single-Center Cohort
Kidney International ReportsIntroduction: In pediatric patients, monogenic causes are a significant contributor to kidney disease, ranging from approximately 10% in congenital anomalies of the kidney and urinary tract (CAKUT) to about 55% in renal ciliopathies. Exome sequencing has
Katharina Lemberg +23 more
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GRcalculator: an online tool for calculating and mining dose–response data
BMC Cancer, 2017 Background Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a means to study factors that contribute to sensitivity and resistance. In dividing cells,
Nicholas A. Clark +8 more
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Estimation of magnitudes of debris flows in selected torrential watersheds in Slovenia [PDF]
, 2006 In this paper the application of different methods for estimation of magnitudes of rainfall-induced debris flows in 18 torrents in the Upper Sava River valley, NW Slovenia, and in 2 torrents in Pohorje, N Slovenia is described. Additional verification of
Mikoš, Matjaž, Sodnik, Jošt
core +2 more sources
Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma +9 more
wiley +1 more source
Frontiers in Human Neuroscience, 2010 Selective optogenetic drive of fast spiking interneurons (FS) leads to enhanced local field potential (LFP) power across the traditional gamma frequency band (20-80Hz; Cardin et al., 2009).
Dorea Vierling-Claassen +4 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 The activity and fate of heavy metals (HMs) from mining and smelting activities in farmland soil is of great significance to effectively prevent the excessive enrichment of HMs in crops.
Bihong He +7 more
doaj +1 more source