Results 101 to 110 of about 293,402 (335)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Emergence and Evolution of Anthropogenic Landscapes in the Western Mediterranean and Adjacent Atlantic Regions

Fire, 2019
Socio-ecological systems are complex, dynamic structures driven by cross-scale interactions between climate, disturbance and subsistence strategies. We synthetize paleoecological data to explore the emergence and evolution of anthropogenic landscapes in ...
Virginia Iglesias, Boris Vannière, Isabelle Jouffroy-Bapicot   +2 more
doaj   +1 more source

Impact of the Mid-Pleistocene Revolution and Anthropogenic Factors on the Dispersion of Asian Black-Spined Toads (Duttaphrynus melanostictus)

Animals, 2020
Divergence-time estimation critically improves the understanding of biogeography processes underlying the distribution of species, especially when fossil data is not available.
Siti N. Othman, Yi-Huey Chen, Ming-Feng Chuang, Desiree Andersen, Yikweon Jang, Amaël Borzée   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Middle and late Holocene vegetation and landscape evolution of the Scheldt estuary : a palynological study of a peat deposit from Doel (Belgium) [PDF]

, 2011
Local and regional environmental conditions for the south-eastern Scheldt estuary during the middle and late Holocene period have been reconstructed based on pollen analysis, loss-on-ignition and radiocarbon dating of a sediment core from Doe (N-Belgium)
Deforce, Koen
core   +1 more source

Bunker Cave stalagmites: an archive for central European Holocene climate variability [PDF]

, 2012
Holocene climate was characterised by variability on multi-centennial to multi-decadal time scales. In central Europe, these fluctuations were most pronounced during winter. Here we present a record of past winter climate variability for the last 10.8 ka
Fohlmeister, Jens, Gerdes, Axel, Immenhauser, Adrian, Mangini, Augusto, Mudelsee, Manfred, Richter, Detlev K., Riechelmann, Dana F. C., Riechelmann, Sylvia, Scholz, Denis, Schröder-Ritzrau, Andrea, Spötl, Christoph, Wackerbarth, Anne Katrin   +11 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

North Atlantic marine ¹⁴C reservoir effects: implications for late-Holocene chronological studies [PDF]

, 2009
We investigated surface ocean–atmosphere 14C offsets for the later Holocene at eight locations in the eastern North Atlantic. This resulted in 11 new ΔR assessments for the west coast of Ireland, the Outer Hebrides, the north coast of the Scottish ...
A.J. Dugmore, Aitken, Ascough, Ascough, Ascough, Ascough, Ascough, Ashmore, Austin, Barrett, Broecker, Bronk Ramsey, Bronk Ramsey, Campin, Church, Culleton, Dugmore, Dye, Eiríksson, Eiríksson, Forman, G.T. Cook, Grove, Harkness, Heier-Neilsen, Hughen, Jiang, Jones, Knight, Kovanen, Lamb, Mangerud, McGovern, McKay, Mook, P.L. Ascough, Paull, Reimer, Reimer, Siani, Siani, Slota, Southon, Spiker, Stuiver, Stuiver, Stuiver, Ulm, Vandeputte, Waelbroeck, Ward, Yoneda   +51 more
core   +1 more source

Arid Central Asia saw mid-Holocene drought

Geology, 2019
The mid-Holocene hydroclimates and the forcing mechanisms over arid Central Asia (ACA) are hotly debated in the context of global climate change. It is widely assumed that ACA Holocene precipitation broadly followed and/or was out-of-phase with Northern ...
Hai Xu, K. Zhou, Jianghu Lan, Guilin Zhang, Xinying Zhou   +4 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source