Results 121 to 130 of about 240,870 (365)

Book review: From the Pleistocene to the Holocene

Journal of Lithic Studies, 2016
From the Pleistocene to the Holocene, edited by Bousman and Vierra, resets our thinking on the pace and overall patterns of transitions in North America at this time.
John Edward Dockall
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Holocene carbon-cycle dynamics based on CO2 trapped in ice at Taylor Dome, Antarctica [PDF]

, 1999
A high-resolution ice-core record of atmospheric CO2 concentration over the Holocene epoch shows that the global carbon cycle has not been in steady state during the past 11,000 years.
Blunier, T., Deck, B., Fischer, Hubertus, Indermühle, A., Joos, F., Mastroianni, D., Meyer, R., Smith, J., Stauffer, B., Stocker, T. F., Tschumi, J., Wahlen, M.   +11 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Postglacial relative sea level change at Fildes Peninsula, King George Island (West Antarctic)

Лëд и снег, 2016
Analysis and integration of data obtained in our field and laboratory investigations of 2008–2012 together with results of previous paleogeographic studies were conducted to reveal parameters and factors of the post-glacial changes in the relative sea ...
K. V. Polishchuk, S. R. Verkulich, I. S. Ezhikov, Z. V. Pushina   +3 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Evaluation of GPR capabilities in the study of seismogenic faulting and deformation in the bottom sediments of Lake Upoloksha (northeast of the Fennoscandian shield)

Геодинамика и тектонофизика, 2018
The article describes the experience of using the GPR method to study the bottom sediments of Lake Upoloksha located in the Kola Peninsula, Russia. Such sediments are viewed as good archives of various Holocene geodynamic processes, including tectonic ...
A. I. Rodionov, S. B. Nikolaeva, P. A. Ryazantsev   +2 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ON THE FORMATION AND DEVELOPMENT OF THE MAMMALIAN FAUNA OF THE EAST BALTIC IN THE HOLOCENE [PDF]

, 1969
K Paaver
openalex   +1 more source